Results 131 to 140 of about 1,648,291 (376)

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

PROSPECTIVE STUDY TO COMPARE RESULTS OF THYROID FUNCTION TESTS OF FLUORESCENT IMMUNOASSAY(FIA) AND ENZYME LINKED RADIOIMMUNOASSAY(ELISA) WITH GOLD STANDARD CHEMILUMINISCENCE TEST(CLIA) TEST IN A TERTIARY CARE HOSPITAL

, 2023
Prerna Nandedkar, Shrinivas Chitta, Kumud Namdeorao Harley, Suresh Ghangale, Neelima Raj   +4 more
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Congenital Hypothyroidism; is There any Familial Component?

مجله دانشکده پزشکی اصفهان, 2009
Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study
Nasibeh Hasani, Bahar Dehghan, Masood Amini, Kamal Heidari, Ali Sajadi, Ali Ajami, Masoomeh Dastanpour, Rezvaneh Hadian, Ashraf Aminoroaya, Zahra Pournaghshband, Silva Hovsepian, Mahin Hashemipour   +11 more
doaj  

Relation between Thyroid Function Tests and Body Mass Index among Thyroid Dysfunction Patients

UHD Journal of Science and Technology
Background: Obesity has the potential to impact thyroid function through various pathways, even in individuals considered euthyroid. The relationship between thyroid function and body mass index (BMI) remains a subject of ongoing debate.
Sanaa Othman Karim, Kalthum Mohammed Gharib, Maisam Hama Murad Majeed, Hadeel Abdulelah Ibrahim, Bayan Omar Sharif, Diman F. Salih, Balen F. Hamasaeed   +6 more
doaj   +1 more source

Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]

, 2019
学位記番号 ...
Matsumoto, Ryutaro, マツモト, リュウタロウ, 松本, 隆太郎   +2 more
core  

Investigating the association of rs2910164 with cancer predisposition in an Irish cohort. [PDF]

, 2017
IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA).
Bell, M, Guerin, C, Kerin, MJ, Lowery, AJ, McVeigh, TP, McVeigh, UM, Miller, N, Mulligan, RJ, Owens, PW, Quill, DS, Sebag, F, Weidhaas, JB   +11 more
core   +3 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Discriminant value of thyroid function tests. [PDF]

, 1973
Julie Jørgensen
openalex   +1 more source

Challenges in Interpretation of Thyroid Function Tests in Pregnant Women with Autoimmune Thyroid Disease

Journal of Thyroid Research, 2011
Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is
U. Feldt-Rasmussen, Anne-Sofie Bliddal Mortensen, Å. Rasmussen, M. Boas, L. Hilsted, K. Main   +5 more
semanticscholar   +1 more source