Results 141 to 150 of about 1,648,291 (376)

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

Thyroid Hormones and Interference in Thyroid Function Tests: A Review

open access: yesJournal of Applied Sciences and Environmental Management
The objective of this paper was to provide a critical and concise review on thyroid hormones and what constitutes interference in thyroid function tests using appropriate Online resources.Thethyroid function tests, play a valuable and significant role ...
O. O. Edet   +4 more
doaj  

Urinary phthalate and thyroid function tests in Hashimoto’s thyroiditis

open access: yesThe Egyptian Journal of Internal Medicine
Background Although Hashimoto’s thyroiditis was recognized over a century ago, its precise cause is still unclear. There are raised concerns that plasticizers like phthalate are related to exacerbation of HT.
Salah Hussien Elhalwany   +5 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Pitfalls in interpreting thyroid function tests: antibodies causing assay interferences

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2015
Many factors can compromise results of thyroid function tests, leading to possible misinterpretation and misdiagnosis. Presence of antibodies in the human serum can react with the immunoglobulins included in the assay components and cause anomalous ...
S. Pathmanathan   +2 more
doaj   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard   +8 more
wiley   +1 more source

Hyperthyroidism in cats, part I : anatomy, physiology, pathophysiology, diagnosis and imaging [PDF]

open access: yes, 2016
In the first part of this review article, thyroid anatomy, physiology and pathophysiology are reviewed to continue more specifically on hyperthyroidism, the most common thyroid disorder in cats.
Daminet, Sylvie   +4 more
core   +1 more source

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