Results 71 to 80 of about 1,648,291 (376)

Monitoring thyroid function status in elderly patients on amiodarone [PDF]

open access: yes, 2006
Objectives: To evaluate whether elderly patients on amiodarone were having their thyroid function status monitored as recommended in the literature and to identify the frequency and type of thyroid function test abnormalities noted.
Fiorini, Anthony
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

open access: yesJournal of Lumbini Medical College, 2017
Introduction: Thyroid dysfunction stands as the second most common endocrine disease after diabetes mellitus. National reports on its prevalence are meagre.
Raj Krishna Dangol   +2 more
doaj   +1 more source

Thyroid Dysfunction following Radiotherapy and Combined Therapy in Non-Thyroid Head and Neck Cancers

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2023
INTRODUCTION: In patients with head and neck cancers thyroid gland bears the brunt in terms of either excision or irradiation resulting in loss of functionality of the gland leading to thyroid dysfunction.
Rais Ahmad Bhat   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Atypical Thyroid Function Tests, Thyroid Hormone Resistance [Atipik Tiroid Fonksiyon Testleri: Tiroid Hormon Direnci]

open access: yesMedicine Science, 2014
The assessment of thyroid function tests for to the diagnose hyperthyroidism (thyrotoxicosis) or hypothyroidism does not constitute a nuisance when the clinical suspicion is strong.
Soner Cander, Ozen Oz Gul, Canan Ersoy
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Postpartum depression and thyroid dysfunction– should pregnant women be screened for thyroid disorders? [PDF]

open access: yes, 2019
The relationship between thyroid dysfunction and postpartum depression has been investigated for quite some time now, but no consensus has been reached regarding the need for screening for thyroid function during pregnancy. This paper aims to investigate
Marin, Erika, Simionescu, Anca A
core   +1 more source

Relation of Prediabetes and Thyroid Function Tests [PDF]

open access: diamond, 2021
Nurhan SAYACA   +2 more
openalex   +1 more source

The clinical use of thyroid function tests.

open access: yesArquivos brasileiros de endocrinologia e metabologia, 2013
Laboratory tests are essential for accurate diagnosis and cost-effective management of thyroid disorders. When the clinical suspicion is strong, hormonal levels just confirms the diagnosis.
G. Carvalho, C. Perez, L. Ward
semanticscholar   +1 more source

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