Results 91 to 100 of about 573,365 (304)

Ultrasonographic Features and the Diagnostic Role of Core Needle Biopsy at Metastatic Breast Cancer in the Thyroid gland: A Case Report

open access: yes대한영상의학회지, 2020
Metastases to the thyroid gland have rarely been reported in clinical settings, and the thyroid gland is an uncommon site for breast carcinoma metastasis.
Dong Hyun Lee   +3 more
doaj   +1 more source

Anaplastic thyroid cancer with transient thyrotoxicosis: Case report and literature review

open access: yes, 1999
A 55-year-old woman with anaplastic thyroid carcinoma presented with hyperthyroidism and neck swelling, hoarseness, and cervical lymphadenopathy.
Alagol, F   +5 more
core   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

open access: yesAdvanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu   +9 more
wiley   +1 more source

Role of Pax8 transcriptional factor in the differentiated thyroid [PDF]

open access: yes, 2010
In Pax8-/- mice the thyroid anlage disappears around E11.5. At birth the gland appears as a rudimentary structure composed only of C cells while thyroid follicular cells are undetectable. Thus, this model does not allow the study of Pax8 function in the
Marotta, Pina
core   +1 more source

GALNT1 emerges as a potential therapeutic target in breast cancer

open access: yesJournal of Cancer Research and Clinical Oncology
Purpose GALNT1, a key enzyme mediating O-GalNAc glycosylation, has not been fully characterized in the tumor microenvironment. This study aimed to investigate its expression pattern, molecular mechanisms, and clinical relevance in breast cancer.
Jiafu Li   +6 more
doaj   +1 more source

Does Papillary Carcinoma of Thyroglossal Duct Cyst Develop De Novo?

open access: yesCase Reports in Otolaryngology, 2015
Backround. Thyroglossal duct cyst (TDC) is a developmental abnormality of the thyroid gland. Due to embryological remnants of thyroid tissue located in the TDC, the same malignant tumors that develop in the thyroid gland can also develop in the TDC ...
Tekin Baglam   +5 more
doaj   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

open access: yesAdvanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji   +11 more
wiley   +1 more source

Parathyroid Double Adenoma Associated with Papillary Carcinoma of Thyroid [PDF]

open access: yes
It has been reported that thyroid disease is common in patients with hyperparathyroidism, and vice versa. Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT).
دادخواه, مینو   +3 more
core  

VCP‐Regulated LMF2 Stabilizes the Cholesterol Biosynthesis Enzyme HMGCS1 to Drive Cancer Progression and Confer Capecitabine Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
LMF2 drives progression and capecitabine resistance in triple‐negative breast cancer (TNBC). Mechanistically, VCP prevents NBR1‐mediated autophagic degradation of LMF2, thereby stabilizing it. Stabilized LMF2 subsequently suppresses NDP52‐mediated autophagic degradation of HMGCS1, a rate‐limiting cholesterol biosynthesis enzyme.
Qian Zhao   +12 more
wiley   +1 more source

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