Results 81 to 90 of about 573,365 (304)

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

The Administration of Thyroid Gland [PDF]

The American Journal of the Medical Sciences, 1896
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openaire   +2 more sources

Informativeness of the Preoperative Examinations in Patients with Small Focal Lesions of the Thyroid Gland

, 2015
Introduction. Doctors of various specialties – endocrinologists, endocrine surgeons, oncologists – pay much attention to the choice of tactics of treatment of small focal forms of thyroid gland. However, despite the tangible progress, the transition to a
Kebkalo А., Reyti A.
core   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Thyroid Abscess in Immuno Compromised Patient: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2012
Thyroid abscess is a rare condition of the thyroid gland. The ability of thyroid gland is to resist infection which is well known and the infection in thyroid gland is rare, particularly so with the advent of widespread usage of antibiotics.
YAMANUR P. LAMANI, S.I. BASARKOD, S.R. TELKAR, B.V. GOUDAR, UDAY AMBI   +4 more
doaj  

Assessment of tear-evaporation rate in thyroid-gland patients

, 2019
Ali Abusharaha,1 Abdulaziz A Alturki,1 Saud A Alanazi,1 Raied Fagehi,1 Naji Al-Johani,2 Gamal A El-Hiti,1 Ali M Masmali1 1Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia; 2Department of ...
El-Hiti GA, Alanazi SA, Masmali AM, Al-Johani N, Abusharaha A, Fagehi R, Alturki AA   +6 more
core  

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Interobserver agreement of Thyroid Imaging Reporting and Data System (TIRADS) and strain elastography for the assessment of thyroid nodules [PDF]

, 2013
Background: Thyroid Imaging Reporting and Data System (TIRADS) was developed to improve patient management and cost-effectiveness by avoiding unnecessary fine needle aspiration biopsy (FNAB) in patients with thyroid nodules.
Stefan Zeuzem, Herrmann, Eva, Friedrich-Rust, Mireen, Dauth, Nina, Bogdanou, Dimitra, Christian Berner, Nina Dauth, Mireen Friedrich-Rust, Bojunga, Jörg, Dimitra Bogdanou, Joerg Bojunga, Gesine Meyer, Eva Herrmann, Berner, Christian, Meyer, Gesine, Zeuzem, Stefan, Friedrich-Rust Mireen, Meyer Gesine, Dauth Nina, Herrmann Eva, Zeuzem Stefan, Bojunga Joerg, Bogdanou Dimitra, Berner Christian   +23 more
core   +2 more sources

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source