Results 51 to 60 of about 308,721 (358)

The mechanism and therapeutic potential of lncRNA MIR497HG/miR-16-5p axis in breast cancer

BMC Women's Health
Background Breast cancer has become a major public health problem in the current society, and its incidence rate ranks the first among Chinese female malignant tumors.
Quan Cheng, Dong-Yang Yu, Yong-Hong Zhou, Jian-Yuan Huang   +3 more
doaj   +1 more source

TCEB2 promotes M2 polarization of macrophages in triple negative breast cancer by mediating ubiquitination degradation of Slit2 through recruiting NEDD4

Translational Oncology
Background: M2-polarized tumor-associated macrophage infiltration is a key risk factor for poor prognosis in triple-negative breast cancer (TNBC). This study investigated the role of transcription elongation factor B polypeptide 2 (TCEB2) in regulating ...
Li Liu, Wang Xiao, Jie Zeng, Jianing Yi, Haoli Gong, Luyao Liu   +5 more
doaj   +1 more source

Dysfunctional ectopic thyroid gland: A case report [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Lingual thyroid gland is a rare anomaly of thyroid gland development, occurring more frequently in females. If it causes local symptomatology such as dysphagia, dysphonia or dyspnea it is diagnosed in childhood, however, if it is ...
Stokić Edita, Kljajić Vladimir, Iđuški Stevan, Benc Damir, Popović Đorđe, Protić Mlađan, Crnobrnja Veljko   +6 more
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Indacenodithienothiophene-based A-D-A-type phototheranostics for immuno-phototherapy

Journal of Nanobiotechnology
The development of phototherapeutics with high photothermal conversion efficiency (PCE) and strong ability to generate reactive oxygen species under single near-infrared (NIR) laser irradiation for immuno-phototherapy applications remains a significant ...
Yangtian Ye, Shaojing Zhao, E Pang, Yuanyu Tang, Pan Zhu, Wenjie Gao, Qingxu Diao, Jie Yu, Jie Zeng, Minhuan Lan, Jianing Yi   +10 more
doaj   +1 more source

Morphological Variations of the Thyroid Gland among the People of Upper Assam Region of Northeast India: A Cadaveric Study [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: The morphological variations of the thyroid gland have been reported from different parts of the world. The variations are due to remnant or non-specific development of the parts of the thyroid gland.
Anjan Jyoti Rajkonwar, Giriraj Kusre
doaj   +1 more source

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

Risk factors and prediction model for lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma

World Journal of Surgical Oncology
Background Metastasis to lymph nodes posterior to the right recurrent laryngeal nerve (LN-prRLN) in papillary thyroid carcinoma (PTC) presents significant surgical challenges due to its deep anatomical location and association with disease recurrence ...
Xiaowen Fang, Jihao Qin, Chenxi Liang, Siyu Li, Xueyu Zeng, Zhu Chen, Jie-Hua Li   +6 more
doaj   +1 more source

Thyroid Gland in Patients with Rheumatoid Arthritis

Клиническая и экспериментальная тиреоидология, 2009
The purpose of our study was to investigate the main parameters of thyroid status in patients with rheumatoid arthritis (RA), as well as particularities of course of this disease depending on of thyroid gland function disorder. Materials and methods.

doaj   +1 more source

Hyperthyroidism in cats, part II : scintigraphic diagnosis and radioiodine treatment [PDF]

, 2016
In the second part of this review article, the diagnostic aspects of thyroid scintigraphy are discussed, with major emphasis on hyperthyroidism, followed by an overview of radioiodine ...
Daminet, Sylvie, Peremans, Kathelijne, Saunders, Jimmy, Vandermeulen, Eva, Volckaert, Veerle   +4 more
core   +1 more source