Results 121 to 130 of about 164,300 (382)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Correlation between umbilical cord concentration of the growth hormone‐IGF axis and small for gestational age: A single‐center retrospective, observational study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Synopsis Imbalance in the GH‐IGF‐1 axis may restrict fetal growth and development, thereby increasing the risk of future metabolic diseases. Abstract Objective To ascertain the association between small for gestational age (SGA) and growth hormone (GH)‐insulin‐like growth factor (IGF) system status.
Jing Wen   +3 more
wiley   +1 more source

Effect of Orexin-A on Cortisol Secretion in H295R Cells via p70S6K/4EBP1 Signaling Pathway

open access: yesInternational Journal of Endocrinology, 2015
Orexin-A is a neuropeptide that orchestrates diverse central and peripheral processes. It is now clear that orexin system plays a central role in the regulation of endocrine, paracrine, and neurocrine.
Xiaocen Chang, Yuyan Zhao, Lei Guo
doaj   +1 more source

Exposure to polybrominated diphenyl ethers (PBDEs) suppresses the release of pro-inflammatory products by alveolar macrophages in vitro [PDF]

open access: yes, 2010
Endocrine disrupting chemicals have adverse effects on immune function that may result in respiratory conditions. Inhalation of dust is a major route of exposure to PBDEs; however, the impact of PBDEs on the immune response is unclear.
Hennigar, Stephen R
core   +1 more source

Pediatric intestinal pseudo‐obstruction found in 3‐year‐old male with Rett‐related mutation of methyl‐CpG binding protein 2

open access: yesJPGN Reports, EarlyView.
Abstract A 3‐year‐old male with chronic abdominal distention, constipation, and severe malnutrition is diagnosed with pediatric intestinal pseudo‐obstruction (PIPO) after extensive evaluation that excluded mechanical, malabsorptive, metabolic, inflammatory, and infectious causes. Aside from speech delay, he has a normal neurologic exam.
Angela Tran, Namrata Patel‐Sanchez
wiley   +1 more source

Vitamin B12 deficiency in a pediatric patient with gastric obstruction and jejunal feeding dependence: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Pediatric B12 deficiency is most caused by insufficient dietary intake, malabsorption or autoimmune gastritis. We present a unique case of B12 deficiency in a pediatric patient with complex gastrointestinal anatomy and jejunal nutritional dependence nearly two decades after unsuccessful surgical intervention.
Angela H. Nguyen   +2 more
wiley   +1 more source

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