ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi +2 more
wiley +1 more source
Thyroid Hormone T3 Induces DNA Damage Response in Breast Cancer Cells. [PDF]
Movshovitz S +6 more
europepmc +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Agreeing Language in Veterinary Endocrinology (ALIVE): Hypothyroidism, Hyperthyroidism, (Euglycaemic) Diabetic Ketosis/Ketoacidosis, and Diabetic Remission-A Modified Delphi-Method-Based System to Create Consensus Definitions. [PDF]
Niessen SJM +15 more
europepmc +1 more source
Cancer Comorbidities: Clinical Impacts, Mechanistic Insights, and Management Strategies
This review focuses on cancer comorbidities, examining their clinical impacts and mechanistic insights. It further examines key management challenges, including evidence gaps, the lack of precise assessment tools, limited management frameworks, and underdeveloped multidisciplinary collaborations.
Taoxing Peng +15 more
wiley +1 more source
Coexistence of familial dysalbuminemic hyperthyroixinemia and papillary thyroid carcinoma: a rare case report and diagnostic challenge. [PDF]
Li Y, Ren M, Lu M, Fan H, Cui D.
europepmc +1 more source
p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor [PDF]
Antonio De Luca +8 more
openalex +1 more source
Supplementing the flushing diet with organic trace minerals based on advanced chelate technology enhanced the reproductive performance of ewes as compared with inorganic trace minerals. ABSTRACT Background The bioavailability of trace minerals (TM) in a diet is important for improving reproductive performance and fertility parameters.
Sedigheh Vatankhah +6 more
wiley +1 more source
Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review. [PDF]
El-Menyar A +7 more
europepmc +1 more source

