Estrogen Receptors as Key Factors in Carcinogenesis. [PDF]
Gruszka O, Jurzak M, Bednarek IA.
europepmc +1 more source
Recurrent Goiter, Hyperthyroidism, Galactorrhea and Amenorrhea due to a Thyrotropin ans Prolactin-Producing Pituitary Tumor [PDF]
Erhardt, F. +5 more
core +1 more source
Single‐cell analysis reveals neuroprotective histone deacetylase inhibitor pathways
Abstract INTRODUCTION Alzheimer's disease (AD) involves β‐amyloid (Aβ) accumulation, tau pathology, and neuroinflammation, driving cognitive decline. Despite extensive research, disease‐modifying therapies remain elusive. We integrated single‐cell RNA sequencing (scRNA‐seq), spatial transcriptomics, and in vitro validation to identify repurposable ...
Madeline Peyton +12 more
wiley +1 more source
Network pharmacology, molecular docking, and molecular dynamics simulations to explore the effects of sinomenine on thyroid dysfunction. [PDF]
Chen J +5 more
europepmc +1 more source
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li +10 more
wiley +1 more source
TET1 loss propels the development of hyperthyroidism by remodeling histone modifications of PAX8 promoter. [PDF]
Dang H +11 more
europepmc +1 more source
A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava +4 more
wiley +1 more source
Expression, immunogenicity and clinical significance analysis of thyroid‑stimulating hormone receptor fusion proteins. [PDF]
Chen X, Chen H.
europepmc +1 more source
ABSTRACT Background Colorectal cancer (CRC) is a leading cause of cancer‐related deaths, with metabolic reprogramming involved in its pathogenesis. Aberrant Arginase 2 (ARG2) expression is linked to malignant progression, but its role in CRC remains unclear. Methods ARG2 expression in CRC and adjacent tissues was analyzed.
Yueyan Zhang +9 more
wiley +1 more source

