Results 281 to 290 of about 164,300 (382)

TSH Ligand‐Based CAR‐T Cell Effectively Eradicates TSHR‐Positive Thyroid Cancer with Favorable Safety Profile

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
TSHR is highly expressed in differentiated thyroid cancer (DTC), making it an ideal target for adoptive immune cell therapy. A novel Ligand‐based TSH‐CAR‐T cell approach effectively eradicated TSHR‐positive thyroid tumors in vitro and accomplished full remission in tumor models with favorable safety profile, highlighting that TSH‐CAR‐T cells could ...
Fei Wang   +10 more
wiley   +1 more source

Effect of ACTH Infusion test on cortisol-4-C14 binding to plasma proteins [PDF]

open access: yes, 1967
Hochheuser, W.   +3 more
core  

Association Between Free Triiodothyronine to Free Thyroxine Ratio and Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Ischemic Stroke Patients

open access: yesBrain and Behavior, Volume 15, Issue 12, December 2025.
The research consecutively enrolled acute ischemic stroke (AIS) patients receiving intravenous thrombolysis (IVT) therapy. A cohort of 251 patients with AIS was recruited at. Clinical information, including free triiodothyronine to free thyroxine (FT3/FT4) from patients, was gathered, and data analysis was conducted.
Haoran Ma   +4 more
wiley   +1 more source

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

open access: yesCancer Communications, Volume 45, Issue 12, Page 1706-1733, December 2025.
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang   +12 more
wiley   +1 more source

Role of Tryptophan Metabolism in Cancer

open access: yesCancer Innovation, Volume 4, Issue 6, December 2025.
This review systematically summarizes the functions and related mechanisms of tryptophan metabolism in various tumor types. It presents the latest progress in this field in a comprehensive manner and combines this with clinical practice to offer a new perspective on tumor treatment.
Zhehao Cui   +5 more
wiley   +1 more source

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