Results 341 to 350 of about 467,905 (403)

Comparison of severe maternal morbidity between pregnancy with subclinical hypothyroidism and overt hypothyroidism

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this cross‐sectional study, pregnancy with subclinical hypothyroidism was associated with higher rates of severe maternal morbidity at delivery compared with overt hypothyroidism, including cardio‐pulmonary morbidity and eclampsia. This association was especially seen among younger age, Black individuals, prepregnant hypertension, and obesity ...
Laurel S. Aberle, Katherine E. Bayard, Kimberly M. Juarez, Jennifer A. Yao, Shinya Matsuzaki, Tatsuya Miyake, Aaron D. Masjedi, Rachel S. Mandelbaum, Caroline T. Nguyen, Joseph G. Ouzounian, Koji Matsuo   +10 more
wiley   +1 more source

Human Milk Practices in Swedish Neonatal Units: Results From a Nationwide Survey

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to describe the routines for handling mother's own milk and donor human milk in Swedish neonatal care units related to national guidelines. Methods A web‐based survey of 24 of 38 neonatal units and 19 of 28 human milk banks in Sweden. Results Despite national guidelines, breast milk handling varied widely.
Ylva Thernström Blomqvist, Anna‐My Lund, Fredrik Ahlsson, Jenny Ericson, Charlotta Karlsson, Josefin Lundström, Ingela Sandström, Anna Gustafsson   +7 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Mutant Thyroid Hormone Receptors and the Potential Effects on Cancer

, 2018
Michael Salomon
openalex   +1 more source

Thyroid Hormone Receptor and Coregulators: A Dynamic Model

, 2019
Xiaopeng Sun
openalex   +1 more source

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Nuclear Receptors for Thyroid Hormone

Journal of Endocrinological Investigation, 1978
The concept that thyroxine (T4) or triiodothyronine (T3) might act by modification of nuclear RNA synthesis was advanced by Tata in the early 1960’s (Tata, Ernster, and Suranyi, 1962). He reported that T4 induced new RNA and protein synthesis, and indicated later that the earliest observable effect was on the function of nuclear magnesium-dependent ...
L J, DeGroot, S, Refetoff, J, Bernal, P A, Rue, A H, Coleoni   +4 more
openaire   +4 more sources

Thyroid Hormone Receptor Gene Knockouts

Trends in Endocrinology & Metabolism, 1998
The thyroid hormone receptor genes, TRalpha and TRbeta, differ in developmental expression and tissue distribution. TRbeta knockout mice have goiter, elevated thyroid hormone and TSH levels, and a functional auditory defect. In contrast, mice with TRalpha 1/alpha2 inactivation have thyroid hypoplasia, low serum thyroid hormone levels, growth arrest and
J H, Hsu, G A, Brent
openaire   +2 more sources

Thyroid Hormone Receptors

1995
Thyroid hormones notably Triiodothyronine (T3) and thyroxine (T4) play important roles in many biological processes in all vertebrates (De Groot et al, 1984). They affect growth, development and differentiation, metabolism and homeostasis. A particularly striking observation was made by Gudernatsch in the early part of this century that thyroid ...
F. Javier Piedrafita, Magnus Pfahl
openaire   +1 more source