Results 121 to 130 of about 2,346,562 (276)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Association between sensitivity to thyroid hormone and prognosis in septic patients: a retrospective cohort analysis

Frontiers in Endocrinology
PurposeSepsis is associated with significant endocrine dysfunction, particularly in thyroid hormone metabolism. This study aims to investigate the association between thyroid hormone sensitivity indices and prognosis in sepsis, exploring their potential ...
Jia Wang, Jia Wang, Yingbai Wang, Yingbai Wang, Zihan Xu, Chuxun Chou, Jiaofeng Xiang, Xizhi Zhang, Xuefei Hou, Xuefei Hou, Suru Yue, Suru Yue, Shicai Ye, Feng Chen, Jiayuan Wu, Jiayuan Wu   +15 more
doaj   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Thyroid-stimulating Hormone and Insulin Resistance: Their Association with Polycystic Ovary Syndrome without Overt Hypothyroidism

, 2017
Objective This study analyzed the effectiveness of the thyroid-stimulating hormone (TSH) as a predictor of insulin resistance (IR) and its association with the clinical and metabolic parameters of women with polycystic ovary syndrome (PCOS) without ...
Cristina Laguna Benetti-Pinto (4661203), Vanessa Berini Piccolo (12726428), Heraldo Garmes (12726431), Daniela Angerame Yela (4661212)   +3 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Impaired sensitivity to thyroid hormones is associated with ASCVD risk factors in Beijing in euthyroid population: a cross-sectional study

Frontiers in Endocrinology
BackgroundThis review aims to investigate the relationship between impaired sensitivity to thyroid hormones and ASCVD risk factors in the euthyroid population.MethodsA cross-sectional study including 7,895 euthyroid subjects aged ≥18 years old was ...
Lintao Shi, Jianjun Wang, Li Yang, Weichao Zhao, Min Zhang, Aiyun Yu, Lingfang Ni, Yu Liu, Haiying Jia   +8 more
doaj   +1 more source

Variant Anatomy Literacy as a Patient‐Safety Competency in Surgical Training: A Title‐Informed Conceptual Review and Competency Framework

Clinical Anatomy, EarlyView.
ABSTRACT Surgical safety depends on recognition of patient‐specific anatomy when encountered structures depart from population norms. Knowledge of anatomical variations is often treated as supplemental rather than as a safety‐relevant necessity.
Juan A. Sanchis‐Gimeno, Andreea‐Bianca Zuld, Mathias Orellana‐Donoso, Juan José Valenzuela‐Fuenzalida, Guinevere Granite   +4 more
wiley   +1 more source

Impaired sensitivity to thyroid hormones is associated with atrial fibrillation in the euthyroid population

Frontiers in Cardiovascular Medicine
BackgroundThe relationship between thyroid hormone sensitivity and atrial fibrillation (AF) progression remains unclear.ObjectiveThis study aimed to investigate the relationship between impaired thyroid hormone sensitivity and the progression of AF in ...
Han Gong, Chun Zhou, Yuanjun Sun, Chengming Ma, Zhipeng Zhang, Yang Liu, Xiaomeng Yin   +6 more
doaj   +1 more source

Anion‐Selective Channels Formed by Synthetic 13‐Mer Chimeric α ‐Peptide‐Oligourea Foldamers

Chemistry – A European Journal, EarlyView.
Synthetic 13‐mer α‐peptide‐oligourea chimeric foldamers self‐assemble into supramolecular ion channels, demonstrating high ion transport activity with distinct anion selectivity in lipid membranes. This study supports the design of bioinspired functional foldamer‐based channels for synthetic ion transport applications.
Chiranjit Dutta, Dandan Su, Pannaga Krishnamurthy, Zhaoxing Li, Jianwei Li, Morgane Pasco, Min Luo, Mihail Barboiu, Gilles Guichard, R. Manjunatha Kini, Prakash Kumar   +10 more
wiley   +1 more source

Association between sensitivity to thyroid hormone indices and chronic kidney disease in US adults from NHANES 2007–2012

Renal Failure
Introduction Thyroid function disorders are prevalent among individuals with chronic kidney disease (CKD). However, the relationship between thyroid hormone sensitivity and CKD remains poorly understood.
Yuanyuan Ye, Shiqun Liu, Shuang Shao, Yian Gu, Xuan Liu, Anting Yu, Ming Liu   +6 more
doaj   +1 more source