Results 161 to 170 of about 71,901 (277)

The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. [PDF]

Front Neurosci, 2021
Martinez ME, Hernandez A.
europepmc   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Association Between Thyroid Hormone Sensitivity Indicators and Controlled Attenuation Parameter (CAP) Values in Euthyroid Adults with Overweight/Obesity. [PDF]

Diabetes Metab Syndr Obes
Zhang Y, Bao C, Liu L, Liu R, Wang X, Guo X, Li C.   +6 more
europepmc   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

Effects of Summer Heat Stress on Physiological Parameters and Reproductive Efficiency of Barbarine Ewes Under Natural Outdoor or Indoor Conditions

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Climate change and rising ambient temperatures increasingly challenge sheep production systems in arid and semi‐arid regions, particularly during the summer breeding season. This study evaluated the effects of heat stress and direct solar exposure on physiological responses, metabolic profile, and reproductive performance of Barbarine ewes, a ...
Samia Khnissi, Dorra Aouadi, Hela Chalouati, Mourad Rekik, Imène Ben Salem   +4 more
wiley   +1 more source

Nonlinear associations of oxidative balance score with central and peripheral thyroid hormone sensitivity: A cross-sectional study of NHANES 2007 to 2012. [PDF]

Medicine (Baltimore)
Wang ZZ, Zhang YH, Xu Q, Zhou J, Song YX, Wang Y, Lv XQ, Hong JF.   +7 more
europepmc   +1 more source

Assessment of Thyroid Uptake Ratio Values in a Normal Population. Establishment of Normal Reference Values for 99mTc‐Pertechnetate Thyroid Uptake in an Australian Population

Journal of Medical Radiation Sciences, EarlyView.
An Australian first, this study examined normal reference ranges for 99mTc‐pertechnetate thyroid uptake. Through a retrospective and prospective analysis, this study found a new reference range of 0.4%–2.4%. The findings suggest that locally derived reference values may differ from historical data and highlight the importance of region‐specific ...
Bethany Wornes, Amalia Karahalios, Melanie Tempest   +2 more
wiley   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person, Jeffrey S. Hyams, Rinarani M. Sanghavi, Valentina Shakhnovich, Katherine Kosch, Moming Li, Danielle D'Achino, Julie Khlevner, Bruno P. Chumpitazi, Miguel Saps   +9 more
wiley   +1 more source