Results 171 to 180 of about 2,346,562 (276)

The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. [PDF]

Front Neurosci, 2021
Martinez ME, Hernandez A.
europepmc   +1 more source

Dose‐Dependent Efficacy of Radioiodine Therapy in Pediatric Graves’ Disease: A Retrospective Study of Hypothyroidism Risk and the Predictive Role of Thyroid Hormone Parameters

iRADIOLOGY, EarlyView.
RAI therapy demonstrated time‐dependent efficacy in pediatric Graves' disease, with gradually increasing treatment success and hypothyroidism incidence during follow‐up. Higher planned activity (≥ 0.15 mCi/g) was associated with a higher successful rate than lower planned activity (< 0.15 mCi/g), and LASSO analysis identified FT3 and TSH as candidate ...
Xiaoxue Tian, Dan Zhang, Yihui Wang, Lujie Cao, Junpu Jian, Jiangyan Liu, Changping Liang, Yinzhong Wang, Yonghui Chen   +8 more
wiley   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Nonlinear associations of oxidative balance score with central and peripheral thyroid hormone sensitivity: A cross-sectional study of NHANES 2007 to 2012. [PDF]

Medicine (Baltimore)
Wang ZZ, Zhang YH, Xu Q, Zhou J, Song YX, Wang Y, Lv XQ, Hong JF.   +7 more
europepmc   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Thyroid hormones and thyroid hormone sensitivity indices correlate with volumetric bone mineral density and vertebral fracture risk among the osteoporotic population in northern China. [PDF]

Front Endocrinol (Lausanne)
Meicen Z, Wei D, Yanai W, Lili H, Tan G, Jia C.   +5 more
europepmc   +1 more source

Case report: Over-substitution of thyroxine due to interference in serum thyroid-stimulating hormone measurement [PDF]

, 2009
Schollen, Annette, Vogeser, Michael, Spitzweg, Christine   +2 more
core   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Dose‐Related Gastric Toxicity of Diethyl Phthalate in Female Wistar Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diethyl phthalate (DEP) is commonly used in cosmetics, personal care products, and pharmaceutical formulations as a low‐molecular‐weight phthalate. Despite its widespread use, information on its effects on the gastric mucosa remains limited. This study examined the dose‐related effects of DEP on inflammation, oxidative stress, gastric mucosal ...
Gul Sahika Gokdemir, Mehmet Cihan Yavaş, Selim Demirtaş, Fazile Cantürk Tan, Salih Varol, Mehmet Tahir Gokdemir   +5 more
wiley   +1 more source