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Functional sensitivity of seven automated thyroid stimulating hormone immunoassays

Clinica Chimica Acta, 2011
Serum thyroid stimulating hormone (TSH) measurements are useful for detecting clinical and subclinical primary hypo- and hyperthyroidism in ambulatory patients. For diagnosis of hyperthyroidism, the functional sensitivity (FS) is an important performance criterion, and current guidelines recommend an FS of ≤0.02 m IU/l for "third" generation ...
William E, Owen   +4 more
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Relation between phenotype and intra‐cellular thyroid hormone effect in patients with altered peripheral thyroid hormone sensitivity

Clinical Endocrinology, 1993
SummaryOBJECTIVE We wished to ascertain whether different phenotypic appearances in patients with altered cellular sensitivity to thyroid hormones were related to the type of altered intra‐cellular thyroid hormone effect.DESIGN Blood samples were obtained from two members of a family suffering from generalized thyroid hormone resistance (GTHR) for ...
J, Kvetny, J, Bollerslev
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A Sensitive Thyroid Stimulating Hormone Assay for Screening of Thyroid Functional Disorder in Elderly Japanese

Journal of the American Geriatrics Society, 1989
The use of a screening test for thyroid functional disorder by sensitive thyroid stimulating hormone assay in the elderly was investigated. The basal thyroid stimulating hormone levels predicted the response of thyroid stimulating hormone to thyrotropin releasing hormone; it was suppressed in 99 (99.0%) of 100 hyperthyroid patients. Therefore, not only
K, Okamura   +7 more
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Differentiation and thyroid‐stimulating hormone (TSH) sensitivity of the fetal rat thyroid in organ culture

The Anatomical Record, 1986
AbstractThyroids from rat fetuses of different ages (from day 14 to day 19 of gestation) were transplanted to organ culture for 2 days, with or without added thyroid‐stimulating hormone (TSH) in the medium. Thyroid tissue from 14‐day fetuses that initially consisted of irregularly arranged cell cords did not form follicles when cultured in the presence
M, Yamamoto   +3 more
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Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy

Clinical Chemistry and Laboratory Medicine (CCLM), 2005
AbstractWe examined insulin sensitivity and secretion, together with the levels of selected glucoregulatory hormones, in 15 female patients with severe hypothyroidism (H) and during subsequent thyroid hormone replacement therapy (HRT) using the euglycaemic hyperinsulinaemic clamp technique.
Sona, Stanická   +5 more
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Simple and sensitive test for thyroid hormone autoantibodies.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1997
We presented a simple and sensitive test for thyroid hormone autoantibodies. The normal range for T4 and T3 autoantibodies in Thai people considering mean +/- 3 S.D. were 1.8-9.4 per cent and 3.1-8.6 per cent, respectively. Although positive low titer of thyroid hormone autoantibodies had almost no interference of thyroid hormone levels, high titer ...
T, Sunthornthepvarakul   +6 more
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Central sensitivity to thyroid hormone indices and glucose metabolism disorders

Clinica Chimica Acta
The central sensitivity to thyroid hormone shows the negative feedback capacity of free thyroxine levels to the pituitary gland. Clinical studies have continuously demonstrated the correlation between the central sensitivity to thyroid hormone and impaired glucose metabolic homeostasis,and positive or negative relationship were found. Different indices
Yue, Zhang, Shuang, Wang, Ping, Li
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SENSITIVE TEST FOR THYROID HORMONE AUTOANTIBODIES IN SERUM

The Lancet, 1982
D J, Allan   +5 more
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Periods of Sensitivity to Thyroid Hormone during the Development of the Organ of Corti

Acta Oto-Laryngologica, 1986
Cochlear structures are sensitive to the morphogenetic effect of thyroid hormone during the whole duration of maturation. For each structure, there exists a period of maximal sensitivity to thyroid hormone which corresponds to the period of development during which the structure of interest undergoes its main morphological changes (6 to 13 days for the
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Sensitivity of thyroid follicular cells to steroid hormones

2000
The results obtained during the studies on the effects of gonadal steroids on thyroid follicular cells (FC) of rats and pigs are summarized. The influence of a single (mg/animal) or double dose of estradiol-dipropionate (EDP) administered in different phases of male and female rat development was studied using cyto logical and stereological methods.
Sekulić, Milka I., Lovren, Mirjana B.
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