Results 1 to 10 of about 202,300 (118)
Prematurity is associated with altered central thyroid hormone sensitivity. [PDF]
Front Endocrinol (Lausanne)ObjectivesThyroid Feedback Quantile-based Index (TFQI), the Thyrotropin–Thyroxine Resistance Index (TT4RI), and the Thyrotropin Index (TSHI) have been developed to assess central sensitivity to thyroid hormones by integrating circulating thyroid hormone ...
Arslan G +5 more
europepmc +2 more sources
Association of impaired sensitivity to thyroid hormone with low bone mineral density and bone mineral content. [PDF]
Front Endocrinol (Lausanne)Osteoporosis is a systemic condition characterized by reduced bone mineral density (BMD) and bone mineral content (BMC), with its global prevalence increasing annually.
Meng G +6 more
europepmc +2 more sources
Main Factors Involved in Thyroid Hormone Action
Molecules, 2021 The thyroid hormone receptors are the mediators of a multitude of actions by the thyroid hormones in cells. Most thyroid hormone activities require interaction with nuclear receptors to bind DNA and regulate the expression of target genes. In addition to
Lorena Tedeschi +3 more
doaj +1 more source
Graves’ disease coexisted with resistance to thyroid hormone: a case report
Journal of Medical Case Reports, 2021 Background Resistance to thyroid hormone is a rare autosomal dominant disorder characterized by reduced responsiveness to thyroid hormone and can cause syndrome of inappropriate secretion of thyroid stimulating hormone.
Hiroshi Akahori, Rika Usuda
doaj +1 more source
Reduced pituitary size in subjects with mutations in the THRB gene and thyroid hormone resistance
Endocrine Connections, 2022 Background: Thyroid hormone action is mediated by two forms of thyroid hormone receptors (α, β) with differential tissue distribution. Thyroid hormone recepto r β (TRβ) mutations lead to resistance to thyroid hormone action in tissues predominantly ...
Marcus Heldmann +11 more
doaj +1 more source
Therapeutic Advances in Endocrinology and Metabolism, 2021 Purpose: To investigate the effect of subclinical hypothyroidism on pregnancy outcomes of women early in their pregnancy with different thyroid-stimulating hormone levels and thyroid peroxidase antibody–negative status and to explore reasonable thyroid ...
Ping Zhu +5 more
doaj +1 more source
BMC Endocrine Disorders, 2023 Background The association between thyroid hormone sensitivity and thyroid cancer is unknown, and we aimed to investigate the association between sensitivity to thyroid hormone indices and papillary thyroid carcinoma (PTC) in Chinese patients with ...
Jie Sun +4 more
doaj +1 more source
European Thyroid Journal, 2023 Objective: Central sensitivity of thyroid hormone refers to the sensitivity of hypothalamic– pituitary–thyroid (HPT) axis to the change in circulating free thyroxine (fT4).
Ying Sun +6 more
doaj +1 more source
European Thyroid Journal, 2023 Thyroid hormones play an essential role in regulating whole-body homeostasis. Deiodinases are known to convert thyroid hormone from the prohormone thyroxine (T4) to the bioactive hormone tri-iodothyronine (T3) and convert both T4 and T3 toward their ...
Eveline Bruinstroop +2 more
doaj +1 more source
Frontiers in Endocrinology, 2022 IntroductionA mathematical model of the pituitary-thyroid feedback loop is extended to deepen the understanding of the Allan-Herndon-Dudley syndrome (AHDS). The AHDS is characterized by unusual thyroid hormone concentrations and a mutation in the SLC16A2
Tobias M. Wolff +5 more
doaj +1 more source