Results 21 to 30 of about 224,446 (313)

Cooperative Subtype Switch of Thyroid Hormone Receptor and Nuclear Receptor Corepressor Related Epithelial–Mesenchymal Transition in Papillary Thyroid Cancer [PDF]

open access: yes, 2021
Background and Objectives: Although thyroid hormones affect human cancer progression, the regulatory mechanism of thyroid hormone receptors in carcinogenesis has not been elucidated.
이잔디   +4 more
core   +1 more source

External radiotherapy of thyroid cancer [PDF]

open access: yes, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
core   +1 more source

Thyroid Hormones and Mitochondria

open access: yesBioscience Reports, 2002
Because of their central role in the regulation of energy-transduction, mitochondria, the major site of oxidative processes within the cell, are considered a likely subcellular target for the action that thyroid hormones exert on energy metabolism. However, the mechanism underlying the regulation of basal metabolic rate (BMR) by thyroid hormones still ...
GOGLIA F., SILVESTRI E., LANNI, Antonia
openaire   +3 more sources

The Syndromes of Resistance to Thyroid Hormone Beta

open access: yes罕见病研究, 2023
The syndrome of resistance to thyroid hormone(RTH) is a rare syndrome caused by the mutation of thyroid hormone receptor (TR) gene, which reduces the sensitivity of target organs to thyroid hormone (TH) and leads to the dysfunction of TH. Thyroid hormone
WANG Huangman   +2 more
doaj   +1 more source

TRH: Pathophysiologic and clinical implications [PDF]

open access: yes, 1985
Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
Pickardt, C. R., Scriba, Peter Christian
core   +1 more source

Thyroid Hormones and Mesotherapy [PDF]

open access: yesFrontiers in Endocrinology, 2011
Thyroid hormones are the master regulator of body metabolism and growth. They act at molecular level to manipulate genes and cellular functions to balance the basic metabolic rate. They bind to superfamily of nuclear receptors that recognize discrete sequences of DNA and act as transcription factors (Renkawitz et al., 1996).
openaire   +3 more sources

Thyroid hormone upregulates zinc-α2-glycoprotein production in the liver but not in adipose tissue. [PDF]

open access: yesPLoS ONE, 2014
Overproduction of zinc-α2-glycoprotein by adipose tissue is crucial in accounting for the lipolysis occurring in cancer cachexia of certain malignant tumors.
Rafael Simó   +5 more
doaj   +1 more source

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

open access: yes, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
Mohammed Elsalanty   +19 more
core   +1 more source

Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses

open access: yesBMC Genomics, 2011
Background Disruption of thyroid hormone signalling can alter growth, development and energy metabolism. Thyroid hormones exert their effects through interactions with thyroid receptors that directly bind thyroid response elements and can alter ...
Paquette Martin A   +6 more
doaj   +1 more source

Whole-genome sequence-based analysis of thyroid function. [PDF]

open access: yes, 2015
Normal thyroid function is essential for health, but its genetic architecture remains poorly understood. Here, for the heritable thyroid traits thyrotropin (TSH) and free thyroxine (FT4), we analyse whole-genome sequence data from the UK10K project (N=2 ...
Paternoster, Lavinia   +635 more
core   +1 more source

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