Results 1 to 10 of about 121,615 (309)

Steroid and Thyroid Hormone Receptors

Endocrinology and Metabolism Clinics of North America, 1991
The identification, cloning, and characterization of steroid and thyroid hormone receptors have revealed much about the mechanisms of hormone action. While their remarkable similarities reflect evolutionary conservation of useful structural and functional motifs, differences in their gene number and organization, mRNA regulation, nuclear localization ...
openaire   +2 more sources

Frequency of Dyslipidemia in Patients Having Subclinical Hypothyroidism

Journal of Gandhara Medical and Dental Sciences, 2016
INTRODUCTION Thyroid hormone by binding to the thyroid hormone receptors affects metabolism and growth in nearly all tissues of the body. Thyroid hormones play vital role in the synthesis and metabolism of lipids. The reduced secretion of thyroxine (T4)
Shah Zeb, Shafaq Naz, Najeeb Ullah
doaj   +1 more source

The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR [PDF]

, 2019
1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB).
Biebermann, Heike, Grüters-Kieslich, Annette, Kalveram, Laura, Kleinau, Gunnar, Rivero-Müller, Adolfo, Scheerer, Patrick, Szymańska, Kamila   +6 more
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Thyroid hormone resistance without mutations in thyroid hormone receptor beta

Medical Science Monitor, 2007
Resistance to thyroid hormone (RTH) is a rare autosomal dominant disorder that leads to elevated free thyroid hormone levels in the presence of normal or increased serum thyroid-stimulating hormone (TSH) concentrations if it is generalized because both the pituitary and peripheral tissues are then partially resistant.
Yvonne, Bottcher, Thomas, Paufler, Thomas, Stehr, Frank Ludwig, Bertschat, Ralf, Paschke, Christian A, Koch   +5 more
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The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: Implications for developing new model organisms [PDF]

, 2015
© 2015 Kaur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Antebi, A Aranda, A Bateman, A Daniel, A De Groot, A Heyland, A Le Maire, AC Chung, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Sluder, AK Allen, AM Puinean, Anne E. Lockyer, AP Scott, AP Scott, B Stone, C Shiff, C Thummel, C Tyler, Catherine S. Jones, CB Burge, CJ Carter, CK Glass, CL Hultin, CM Adema, CM Adema, D Bouton, D Jones, D Lima, D Stange, DH Huson, DL Whitehead, E Enmark, Edwin J. Routledge, ER Levin, ES Ford, F Abascal, F Bonneton, F Ronquist, FM Sladek, G Benoit, G Escobedo, G Mitta, GN Eick, GV Markov, GV Markov, H Ueda, H Urushitani, H Zhang, H-R Koehler, I Letunic, J Auwerx, J Gutierrez-Mazariegos, J Keay, J Keay, J Oehlmann, J-M Wurtz, JT Bridgham, JT Bridgham, JW Thornton, K King-Jones, K King-Jones, K Tamura, L Chitsulo, L de F Tallarico, L-M Chen, LA Hertel, Leslie R. Noble, LFC Castro, LFC Castro, LN Rapado, M Garcia, M Kajiwara, M Knight, M Laguerre, M Pawlak, M Robinson-Rechavi, M Robinson-Rechavi, M Robinson-Rechavi, M Tillmann, M-JWA Schiffelers, MD Adams, ME Baker, ME Baker, MI Snow, N Raghavan, NE-SE-S Omran, O Simakov, P Matthiessen, P Matthiessen, P Thomas, PC Hanington, PC Hanington, PD Thomas, Peter P. Fong, PL Bardet, R Bannister, R Bannister, R Lafont, RA Velarde, RJ Greenspan, RM Sternberg, RM Sternberg, RT Yu, S Bertrand, S Kliewer, S Kumkate, S Pascoal, S Vogeler, SA Thomson, Satwant Kaur, SF Altschul, SH Golden, Susan Jobling, T Li, T Matsumoto, T Simoncini, TH Lindblom, TT Schug, W Wu, W Wu, W Wu, W Wu, X Ding, X Mu, Y Katsu, YG Jiang, ZD Zhang   +131 more
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Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]

, 2019
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J, Corbo, Joseph C, Lewis, Victor M, McFaline-Figueroa, Jose L, Mishra, Abhishek K, Packer, Jonathan S, Parichy, David M, Qiu, Xiaojie, Saunders, Lauren M, Toomey, Matthew B, Trapnell, Cole   +10 more
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The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves, D'Herde, Katharina, Diez Fraile, Araceli, Lammens, Tim   +3 more
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Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
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The Effects of Disturbance on Hypothalamus-Pituitary-Thyroid (HPT) Axis in Zebrafish Larvae after Exposure to DEHP.

PLoS ONE, 2016
Di-(2-ethylhexyl) phthalate (DEHP) has the potential to disrupt the thyroid endocrine system, but the underlying mechanism is unknown. In this study, zebrafish (Danio rerio) embryos were exposed to different concentrations of DEHP (0, 40, 100, 200, 400 ...
Pan-Pan Jia, Yan-Bo Ma, Chun-Jiao Lu, Zakaria Mirza, Wei Zhang, Yong-Fang Jia, Wei-Guo Li, De-Sheng Pei   +7 more
doaj   +1 more source

Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos. [PDF]

, 2017
Thyroid hormones are essential for normal brain development in vertebrates. In humans, abnormal maternal thyroid hormone levels during early pregnancy are associated with decreased offspring IQ and modified brain structure.
Affaticati, Pierre, Demeneix, Barbara A., Fini, Jean-Baptiste, Jenett, Arnim, Le Mevel, Sebastien, Leemans, Michelle, Lettmann, Melodie, Mughal, Bilal Babar, Spirhanzlova, Petra   +8 more
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