Results 21 to 30 of about 63,636 (263)
Thyroid hormone receptors and cancer [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2013 Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the actions of the thyroid hormone (T3) in development, growth, and differentiation. The THRA and THRB genes encode several TR isoforms that express in a tissue- and development-dependent manner.
Won Gu, Kim, Sheue-yann, Cheng
openaire +2 more sources
Independent Skeletal Actions of Pituitary Hormones [PDF]
Endocrinology and Metabolism, 2022 Over the past years, pituitary hormones and their receptors have been shown to have non-traditional actions that allow them to bypass the hypothalamus-pituitary-effector glands axis.
Se-Min Kim +5 more
doaj +1 more source
Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]
Endocrine-Related Cancer, 2013 Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
openaire +3 more sources
Thyroid hormone function in the rat testis
Frontiers in Endocrinology, 2014 Thyroid hormones are emerging regulators of testicular function since Sertoli, germ and Leydig cells are found to express thyroid hormone receptors. These testicular cells also express deiodinases which are capable of converting the pro-hormone T4 to the
Ying eGao, Will M. eLee, C Yan eCheng
doaj +1 more source
Frontiers in Endocrinology, 2012 Thyroid disease often causes menstrual disturbances and infertility problems. Thyroid hormone (TH) acts through its receptors, transcription factors present in most cell types in the body.
Anneli eStavreus-Evers
doaj +1 more source
Role of maternal thyroid hormones in the developing neocortex and during human evolution
Frontiers in Neuroanatomy, 2013 The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
doaj +1 more source
Primary hypothyroidism with exuberant dermatological manifestations, [PDF]
Anais Brasileiros de Dermatologia, 2020 Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism.
Thadeu Santos Silva +3 more
doaj +2 more sources
Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo. [PDF]
PLoS ONE, 2017 Ghrelin is a peptide hormone produced mainly in the gastrointestinal tract known to regulate several physiological functions including gut motility, adipose tissue accumulation and hunger sensation leading to increased bodyweight.
Maria Barington +5 more
doaj +1 more source
Reduced expression of thyroid hormone receptor β in human nonalcoholic steatohepatitis
Endocrine Connections, 2018 Hepatic thyroid hormone signaling has an important role in the development and progression of nonalcoholic steatohepatitis (NASH). While the systemic levels of thyroid hormone might remain stable, there is evidence that the intracellular signaling ...
Christin Krause +7 more
doaj +1 more source
Graves’ ophthalmopathy – thyroid eye disease
Journal of Education, Health and Sport, 2019 Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka +3 more
doaj +3 more sources