Results 41 to 50 of about 121,615 (309)
Hormonal regulation of female reproduction [PDF]
, 2012 Reproduction is an event that requires the coordination of peripheral organs with the nervous system to ensure that the internal and external environments are optimal for successful procreation of the species.
Bentley, G. E. +6 more
core +1 more source
Thyroxine-Thyroid Hormone Receptor Interactions [PDF]
Journal of Biological Chemistry, 2004 Thyroid hormone (TH) actions are mediated by nuclear receptors (TRs alpha and beta) that bind triiodothyronine (T(3), 3,5,3'-triiodo-l-thyronine) with high affinity, and its precursor thyroxine (T(4), 3,5,3',5'-tetraiodo-l-thyronine) with lower affinity. T(4) contains a bulky 5' iodine group absent from T(3).
Sandler, Ben +10 more
openaire +3 more sources
Frontiers in Endocrinology, 2014 Cerebellum development is sensitive to thyroid hormone (TH) levels, as THs regulate neuronal migration, differentiation and myelination. Most effects of THs are mediated by the TH receptor (TR) isoforms TRb1, TRb2 and TRa1.
Larissa Costa Faustino +1 more
doaj +1 more source
Diseases, 2020 Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings.
Duaa Althumairy +6 more
doaj +1 more source
Oftalʹmologiâ, 2014 Purpose: To explore the role of thyroid hormone’ receptors in the development of the autoimmune process in orbita.Methods: The intraoperative biopsy material of the lacrimal gland obtained from orbital decompression in patients with autoimmune ...
V. G. Likhvantseva +5 more
doaj +3 more sources
Discovery & development of small molecule allosteric modulators of glycoprotein hormone receptors
Frontiers in Endocrinology, 2015 Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid stimulating hormone (TSH) are heterodimeric proteins with a common subunit and hormone-specific subunit.
Selvaraj G Nataraja +2 more
doaj +1 more source
Thyroid Hormones Play Role in Sarcopenia and Myopathies
Frontiers in Physiology, 2018 Skeletal muscle maintains posture and enables movement by converting chemical energy into mechanical energy, further contributing to basal energy metabolism.
Flavia F. Bloise +3 more
doaj +1 more source
Thyroid Stimulating Hormone Receptor
Molecular Imaging and Radionuclide Therapy, 2017 Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role
openaire +2 more sources
Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis--A Cohort Study in a Group of Thyroid Carcinoma Patients. [PDF]
PLoS ONE, 2016 BACKGROUND/OBJECTIVES:Thyroid hormone receptors are present on brown adipose tissue (BAT), indicating a role for thyroid hormone in the regulation of BAT activation.
Evie P M Broeders +9 more
doaj +1 more source
Evolutionary Adaptation of the Thyroid Hormone Signaling Toolkit in Chordates
Cells, 2021 The specification of the endostyle in non-vertebrate chordates and of the thyroid gland in vertebrates are fundamental steps in the evolution of the thyroid hormone (TH) signaling to coordinate development and body physiology in response to a range of ...
Alfonso Esposito +5 more
doaj +1 more source