Results 31 to 40 of about 121,615 (309)
TSHR (thyroid stimulating hormone receptor) [PDF]
Review on TSHR (thyroid stimulating hormone receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
IOSCO, CARMELA, RHODEN, KERRY JANE
openaire +3 more sources
Graves’ ophthalmopathy – thyroid eye disease
Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka +3 more
doaj +3 more sources
Reduced expression of thyroid hormone receptor β in human nonalcoholic steatohepatitis
Hepatic thyroid hormone signaling has an important role in the development and progression of nonalcoholic steatohepatitis (NASH). While the systemic levels of thyroid hormone might remain stable, there is evidence that the intracellular signaling ...
Christin Krause +7 more
doaj +1 more source
A novel variant of THRβ and its 4-year clinical course in a Korean boy with resistance to thyroid hormone [PDF]
Thyroid hormone resistance (RTH) is characterized by a decreased sensitivity of target tissues to thyroid hormones due to a defect in the THRα- and THRβ-encoded thyroid hormone receptors (THRs).
Sejin Kim +4 more
doaj +1 more source
Thyroid hormone receptors and cancer [PDF]
Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the actions of the thyroid hormone (T3) in development, growth, and differentiation. The THRA and THRB genes encode several TR isoforms that express in a tissue- and development-dependent manner.
Won Gu, Kim, Sheue-yann, Cheng
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Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene [PDF]
Resistance to thyroid hormone (RTH) is a rare inherited syndrome characterized by diminished response of the target tissue to thyroid hormone caused, in the majority of cases, by mutation of the thyroid hormone receptor beta (THRβ) gene. Despite elevated
Jae Hee Lee, Eun Young Kim
doaj +1 more source
Thyroid hormones, T3 (triiodothyronine) and T4 (thyroxine), induce a variety of long-term effects on important physiological functions, ranging from development and growth to metabolism regulation, by interacting with specific nuclear or cytosolic ...
Sandra Incerpi +20 more
doaj +1 more source
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Life Without Thyroid Hormone Receptor [PDF]
Abstract Thyroid hormone (T3) is critical not only for organ function and metabolism in the adult but also for animal development. This is particularly true during the neonatal period when T3 levels are high in mammals. Many processes during this postembryonic developmental period resemble those during amphibian metamorphosis.
openaire +2 more sources
Benzisothiazolinone (BIT), one of the most widely used antimicrobial agents in consumer products, has frequently been detected in the water environment. The present study was conducted to determine the adverse effects of BIT on the thyroid neuroendocrine
Sujin Lee +4 more
doaj +1 more source

