Results 31 to 40 of about 121,615 (309)

TSHR (thyroid stimulating hormone receptor) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on TSHR (thyroid stimulating hormone receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
IOSCO, CARMELA, RHODEN, KERRY JANE
openaire   +3 more sources

Graves’ ophthalmopathy – thyroid eye disease

open access: yesJournal of Education, Health and Sport, 2019
Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka   +3 more
doaj   +3 more sources

Reduced expression of thyroid hormone receptor β in human nonalcoholic steatohepatitis

open access: yesEndocrine Connections, 2018
Hepatic thyroid hormone signaling has an important role in the development and progression of nonalcoholic steatohepatitis (NASH). While the systemic levels of thyroid hormone might remain stable, there is evidence that the intracellular signaling ...
Christin Krause   +7 more
doaj   +1 more source

A novel variant of THRβ and its 4-year clinical course in a Korean boy with resistance to thyroid hormone [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2023
Thyroid hormone resistance (RTH) is characterized by a decreased sensitivity of target tissues to thyroid hormones due to a defect in the THRα- and THRβ-encoded thyroid hormone receptors (THRs).
Sejin Kim   +4 more
doaj   +1 more source

Thyroid hormone receptors and cancer [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2013
Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the actions of the thyroid hormone (T3) in development, growth, and differentiation. The THRA and THRB genes encode several TR isoforms that express in a tissue- and development-dependent manner.
Won Gu, Kim, Sheue-yann, Cheng
openaire   +2 more sources

Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2014
Resistance to thyroid hormone (RTH) is a rare inherited syndrome characterized by diminished response of the target tissue to thyroid hormone caused, in the majority of cases, by mutation of the thyroid hormone receptor beta (THRβ) gene. Despite elevated
Jae Hee Lee, Eun Young Kim
doaj   +1 more source

Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles

open access: yesFrontiers in Endocrinology, 2022
Thyroid hormones, T3 (triiodothyronine) and T4 (thyroxine), induce a variety of long-term effects on important physiological functions, ranging from development and growth to metabolism regulation, by interacting with specific nuclear or cytosolic ...
Sandra Incerpi   +20 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

open access: yes, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland   +4 more
core   +1 more source

Life Without Thyroid Hormone Receptor [PDF]

open access: yesEndocrinology, 2021
Abstract Thyroid hormone (T3) is critical not only for organ function and metabolism in the adult but also for animal development. This is particularly true during the neonatal period when T3 levels are high in mammals. Many processes during this postembryonic developmental period resemble those during amphibian metamorphosis.
openaire   +2 more sources

Thyroid hormone disrupting potentials of benzisothiazolinone in embryo-larval zebrafish and rat pituitary GH3 cell line

open access: yesEcotoxicology and Environmental Safety, 2023
Benzisothiazolinone (BIT), one of the most widely used antimicrobial agents in consumer products, has frequently been detected in the water environment. The present study was conducted to determine the adverse effects of BIT on the thyroid neuroendocrine
Sujin Lee   +4 more
doaj   +1 more source

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