Results 31 to 40 of about 63,636 (263)

Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2014
Resistance to thyroid hormone (RTH) is a rare inherited syndrome characterized by diminished response of the target tissue to thyroid hormone caused, in the majority of cases, by mutation of the thyroid hormone receptor beta (THRβ) gene. Despite elevated
Jae Hee Lee, Eun Young Kim
doaj   +1 more source

Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles

Frontiers in Endocrinology, 2022
Thyroid hormones, T3 (triiodothyronine) and T4 (thyroxine), induce a variety of long-term effects on important physiological functions, ranging from development and growth to metabolism regulation, by interacting with specific nuclear or cytosolic ...
Sandra Incerpi, Fabio Gionfra, Roberto De Luca, Elena Candelotti, Paolo De Vito, Zulema A. Percario, Stefano Leone, Davide Gnocchi, Miriam Rossi, Francesco Caruso, Sergio Scapin, Paul J. Davis, Paul J. Davis, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Elisabetta Affabris, Jens Z. Pedersen   +20 more
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A novel variant of THRβ and its 4-year clinical course in a Korean boy with resistance to thyroid hormone [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2023
Thyroid hormone resistance (RTH) is characterized by a decreased sensitivity of target tissues to thyroid hormones due to a defect in the THRα- and THRβ-encoded thyroid hormone receptors (THRs).
Sejin Kim, Soyun Park, Jungeun Moon, Heungsik Kim, Seokjin Kang   +4 more
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Thyroid hormone disrupting potentials of benzisothiazolinone in embryo-larval zebrafish and rat pituitary GH3 cell line

Ecotoxicology and Environmental Safety, 2023
Benzisothiazolinone (BIT), one of the most widely used antimicrobial agents in consumer products, has frequently been detected in the water environment. The present study was conducted to determine the adverse effects of BIT on the thyroid neuroendocrine
Sujin Lee, Bareum Kwon, Junhyeok Jeong, Younglim Kho, Kyunghee Ji   +4 more
doaj   +1 more source

Thyroid hormone role on cerebellar development and maintenance: a perspective based on transgenic mouse models

Frontiers in Endocrinology, 2014
Cerebellum development is sensitive to thyroid hormone (TH) levels, as THs regulate neuronal migration, differentiation and myelination. Most effects of THs are mediated by the TH receptor (TR) isoforms TRb1, TRb2 and TRa1.
Larissa Costa Faustino, Tania M Ortiga-Carvalho   +1 more
doaj   +1 more source

Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors

Diseases, 2020
Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings.
Duaa Althumairy, Xiaoping Zhang, Nicholas Baez, George Barisas, Deborah A. Roess, George R. Bousfield, Debbie C. Crans   +6 more
doaj   +1 more source

Studying the role of thyroid hormone receptor expression in the lacrimal gland in the autoimmune orbitopathy

Oftalʹmologiâ, 2014
Purpose: To explore the role of thyroid hormone’ receptors in the development of the autoimmune process in orbita.Methods: The intraoperative biopsy material of the lacrimal gland obtained from orbital decompression in patients with autoimmune ...
V. G. Likhvantseva, O. A. Gontyurova, E. A. Rudenko, T. N. Saphonova, K. A. Kuzmin, N. Y. Sviridenko   +5 more
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Discovery & development of small molecule allosteric modulators of glycoprotein hormone receptors

Frontiers in Endocrinology, 2015
Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid stimulating hormone (TSH) are heterodimeric proteins with a common subunit and hormone-specific subunit.
Selvaraj G Nataraja, Henry N Yu, Stephen S Palmer   +2 more
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Thyroid Hormones Play Role in Sarcopenia and Myopathies

Frontiers in Physiology, 2018
Skeletal muscle maintains posture and enables movement by converting chemical energy into mechanical energy, further contributing to basal energy metabolism.
Flavia F. Bloise, Thamires S. Oliveira, Aline Cordeiro, Tania M. Ortiga-Carvalho   +3 more
doaj   +1 more source

Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis--A Cohort Study in a Group of Thyroid Carcinoma Patients. [PDF]

PLoS ONE, 2016
BACKGROUND/OBJECTIVES:Thyroid hormone receptors are present on brown adipose tissue (BAT), indicating a role for thyroid hormone in the regulation of BAT activation.
Evie P M Broeders, Guy H E J Vijgen, Bas Havekes, Nicole D Bouvy, Felix M Mottaghy, Marleen Kars, Nicolaas C Schaper, Patrick Schrauwen, Boudewijn Brans, Wouter D van Marken Lichtenbelt   +9 more
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