A rare mutation of thyroid hormone receptor beta gene in thyroid hormone resistance syndrome [PDF]
Endocrinology, Diabetes & Metabolism Case Reports, 2021 Resistance to thyroid hormone (RTH) is a rare hereditary syndrome with impaired sensitivity to thyroid hormones (TH) and reduced intracellular action of triiodothyronine (T3) caused by genetic variants of TH receptor beta (TRB) or alpha (TRA).
Michela Del Prete +6 more
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Thyroid hormone resistance syndrome due to a novel heterozygous mutation and concomitant Hashimoto’s Thyroiditis: A pedigree report [PDF]
Journal of International Medical Research, 2022 Thyroid hormone resistance syndrome (THRS) is a rare disease characterized by reduced sensitivity to thyroid hormones. Mutations in the thyroid hormone receptor beta ( THRB ) gene are considered as contributing to the pathogenesis.
Zongyan Xie +4 more
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Identification of a novel THRB mutation causing thyroid hormone resistance syndrome [PDF]
Archives of Endocrinology and MetabolismResistance to thyroid hormone syndrome (RTHS) is a rare disorder caused by mutations in the thyroid hormone receptor beta (THRB) gene, resulting in impaired action of thyroid hormones on target tissues and organs.
Jing Yang +3 more
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Correlation between the thyrotropin-thyroxine resistance index and insulin resistance in polycystic ovary syndrome patients with phlegm-dampness syndrome [PDF]
Frontiers in EndocrinologyIntroductionPolycystic ovary syndrome (PCOS) patients classified as the phlegm-dampness syndrome typically suffer from metabolic dysfunction mainly driven by insulin resistance (IR).
Ying Liu +8 more
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The Syndromes of Resistance to Thyroid Hormone Beta
罕见病研究, 2023 The syndrome of resistance to thyroid hormone(RTH) is a rare syndrome caused by the mutation of thyroid hormone receptor (TR) gene, which reduces the sensitivity of target organs to thyroid hormone (TH) and leads to the dysfunction of TH. Thyroid hormone
WANG Huangman +2 more
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Clinical and metabolic links between hypothyroidism and metabolic syndrome: a review [PDF]
Frontiers in EndocrinologyHypothyroidism and metabolic syndrome frequently coexist and share abnormalities in body weight, lipid metabolism, glucose regulation, and inflammatory signaling.
Mubai Li +6 more
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The clinical characteristics and gene mutations associated with thyroid hormone resistance syndrome coexisting with pituitary tumors. [PDF]
Front Endocrinol (Lausanne), 2023 Zhao J +5 more
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Triiodothyroacetic acid exerts tissue-specific thyromimetic effects without tachycardia and hyperthermia in male mice [PDF]
European Thyroid JournalObjective: Thyroid hormones regulate cardiovascular functions and energy homeostasis, including thermogenesis, through binding to nuclear thyroid hormone receptors. The thyroid hormone analog 3,3′,5-triiodothyroacetic acid (TRIAC) has recently emerged as
Beate Herrmann +3 more
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Calcitonin values in pseudohypoparathyroidism [PDF]
Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2023 Pseudohypoparathyroidism type 1A is a rare endocrine disorder caused by GNAS mutation and the resulting hormone resistance at the receptor level, i.e. the activation of the intracellular pathway of the Gs alpha subunit is not possible.
Marković Bojan +6 more
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Graves’ disease coexisted with resistance to thyroid hormone: a case report
Journal of Medical Case Reports, 2021 Background Resistance to thyroid hormone is a rare autosomal dominant disorder characterized by reduced responsiveness to thyroid hormone and can cause syndrome of inappropriate secretion of thyroid stimulating hormone.
Hiroshi Akahori, Rika Usuda
doaj +1 more source