Results 21 to 30 of about 42,240 (230)
ODP521 THYROID HORMONE RESISTANCE SYNDROME [PDF]
J Endocr Soc, 2022 Abstract Introduction The Thyroid hormone resistance syndrome is characterized by decreased tissue sensitivity to thyroid hormones. The incidence is about 1/50,000. We present two clinical cases of this disease. Clinical case 1A 59-year-old woman was evaluated for presenting palpitations for more than
Franco, Katty Manrique, Manrique, Helard
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Syndrome of Resistance to Thyroid Hormone: Insights into Thyroid Hormone Action
Experimental Biology and Medicine, 1996 Thyroid hormones (T3, T4) exert multiple cellular effects through nuclear thyroid hormone receptors (TR alpha, TR beta). Thyroid hormone receptors are transcription factors that act by altering patterns of gene expression. Resistance to thyroid hormone (RTH) is a rare disorder caused by mutations in the TR beta gene.
P, Kopp, K, Kitajima, J L, Jameson
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Trends in Pediatrics, 2023 In children, abnormal thyroid function tests (TFTs) can present diagnostic difficulty due to the variety of clinical manifestations that may accompany them.
Gözde Akın Kağızmanlı, Korcan Demir
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Resistance to Thyroid Hormone Beta: A Focused Review
Frontiers in Endocrinology, 2021 Resistance to thyroid hormone (RTH) is a clinical syndrome defined by impaired sensitivity to thyroid hormone (TH) and its more common form is caused by mutations in the thyroid hormone receptor beta (THRB) gene, termed RTHβ.
Theodora Pappa, Samuel Refetoff
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中国甲状腺功能正常人群对甲状腺激素的敏感性和代谢综合征组分的风险
Journal of Diabetes, 2023 Introduction To evaluate the association of sensitivity to thyroid hormone with metabolic syndrome (MetS) and its components in a Chinese euthyroid population. Methods A total of 3573 participants from Pinggu Metabolic Disease Study were analyzed.
Fang Lv +6 more
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Journal of Medical Case Reports, 2012 Introduction Resistance to thyroid hormone is a syndrome caused by thyroid hormone receptor β mutations, which are usually inherited in an autosomal-dominant pattern.
Yatsuga Shuichi +6 more
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Thyroid Hormone Resistant Syndrome
Medical Journal of Southern California Clinicians, 2020 Thyroid hormone resistance (THR), also known as resistance to thyroid hormone (RTH), is an inherited condition characterized by reduced end-organ responsiveness to thyroid hormone, caused by mutations in the thyroid hormone receptor gene. Patients typically present with elevated thyroid hormone levels (T3 and T4) with normal, or slightly elevated ...
Karo Gyurjian, Vishwanath Venketaraman
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Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors. [PDF]
Journal of Clinical Investigation, 1991 Thyroid hormone (T3) resistance is inherited in most cases in an autosomal dominant manner. The disorder is characterized by elevated free thyroid hormone levels and partial resistance to thyroid hormone at the cellular level. Distinct single amino acid substitutions in the ligand binding domain of the beta form of the thyroid hormone receptor have ...
Chatterjee, V. Krishna K. +5 more
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Syndromes of resistance to thyroid hormone
Clinical and experimental thyroidology, 2013 Синдром резистентности к тиреоидным гормо нам (RTH) является наследственным синдромом, характеризующимся пониженной чувствительнос тью тканеймишеней к гормонам щитовидной желе зы. RTH впервые был описан в 1967 году как часть семейного синдрома, включающего глухонемоту, зоб и аномально повышенный уровень тиреоидных гор монов на фоне нормальной ...
V A Kaldymova, A V Kiyaev, A N Tyulpakov
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