Results 11 to 20 of about 724,472 (302)

Bisphenols and Thyroid Hormone [PDF]

Endocrinology and Metabolism, 2019
In recent decades, attention has been directed toward the effects of bisphenol A (BPA) on human health. BPA has estrogenic activity and is regarded as a representative endocrine disruptor.
Min Joo Kim, Young Joo Park
doaj   +4 more sources

Longitudinal evidence of the impact of normal thyroid stimulating hormone variations on cognitive functioning in very old age [PDF]

, 2008
The purpose of this study was to examine longitudinal associations among thyroid stimulating hormone (TSH) levels and cognitive performance. Data collected at the first three assessment times, approximately 3 years apart, are reported for the survivors ...
Wahlin, TBR, Wahlin, A, Bunce, D
core   +6 more sources

Thyroid Hormone Transporters [PDF]

Biochemical Society Transactions, 2005
Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Friesema, Edith, Jansen, Jurgen, Milici, C, Visser, Theo   +3 more
openaire   +5 more sources

Treatment With Thyroid Hormone [PDF]

Endocrine Reviews, 2014
Thyroid hormone deficiency can have important repercussions. Treatment with thyroid hormone in replacement doses is essential in patients with hypothyroidism. In this review, we critically discuss the thyroid hormone formulations that are available and approaches to correct replacement therapy with thyroid hormone in primary and central hypothyroidism ...
BIONDI, BERNADETTE, Wartofsky L.
openaire   +3 more sources

Thyroid hormone receptors and resistance to thyroid hormone disorders [PDF]

Nature Reviews Endocrinology, 2014
Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs), which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor β (THRB) genes. Patients with mutations in THRB present with resistance to thyroid hormone β (RTHβ), which is a disorder characterized by elevated levels of thyroid hormone, normal
Tânia M, Ortiga-Carvalho, Aniket R, Sidhaye, Fredric E, Wondisford   +2 more
openaire   +2 more sources

Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]

Endocrine-Related Cancer, 2013
Abstract Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
openaire   +3 more sources

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Bergman, A., Berg, J.J.J., van den, van den Berg, J.H.J., Meerts, I.A.T.M., Weijers, B.M., van den Berg, J.J.J., Brouwer, A., Assink, Y., Cenijn, P.H., Berg, J.H.J. van den, Koeman, J.H., Assin, Y.   +11 more
core   +2 more sources

A Case of Thyroid Hormone Resistance Syndrome with a Novel Mutation (c.947G>a) in the THRB Gene: Experience in Diagnosis and Treatment [PDF]

International Medical Case Reports Journal
Jie Liu, Yu Wei, Yanhui Zhu, Yu Li, Qiong Wang, Lei Yu, Langen Zhuang, Guoxi Jin, Xiaoyan Pei Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui Province, People’s Republic of ChinaCorrespondence: Guoxi
Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Yu L, Zhuang L, Jin G, Pei X   +8 more
doaj   +1 more source

A negative correlation of thyroid stimulating hormone with anti_mullerian hormone and with luteinizing hormone in polycystic ovary syndrome and/or hypothyroid women

Middle East Fertility Society Journal, 2018
Background: Using anti_mullerian hormone (AMH) for Polycystic Ovary Syndrome diagnosis is not always constant. Thyroid dysfunction may effect on AMH levels.
Samal Hakeem Kareem AL-Jaff
doaj   +1 more source

Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation. [PDF]

PLoS ONE, 2014
Thyroid hormone entry into cells is facilitated by transmembrane transporters. Mutations of the specific thyroid hormone transporter, MCT8 (Monocarboxylate Transporter 8, SLC16A2) cause an X-linked syndrome of profound neurological impairment and altered
Bárbara Núñez, Raquel Martínez de Mena, Maria Jesus Obregon, Mariona Font-Llitjós, Virginia Nunes, Manuel Palacín, Alexandra M Dumitrescu, Beatriz Morte, Juan Bernal   +8 more
doaj   +1 more source