Results 11 to 20 of about 339,246 (308)
European Thyroid Journal, 2023 Thyroid hormones play an essential role in regulating whole-body homeostasis. Deiodinases are known to convert thyroid hormone from the prohormone thyroxine (T4) to the bioactive hormone tri-iodothyronine (T3) and convert both T4 and T3 toward their ...
Eveline Bruinstroop +2 more
doaj +1 more source
Thyroid Hormone Transporters [PDF]
Endocrine Reviews, 2019 AbstractThyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion transporting polypeptide (OATP) 1C1, and SLC17A4 are currently known as transporters displaying the highest specificity toward thyroid hormones.
Stefan Groeneweg +4 more
openaire +3 more sources
Frontiers in Endocrinology, 2022 IntroductionA mathematical model of the pituitary-thyroid feedback loop is extended to deepen the understanding of the Allan-Herndon-Dudley syndrome (AHDS). The AHDS is characterized by unusual thyroid hormone concentrations and a mutation in the SLC16A2
Tobias M. Wolff +5 more
doaj +1 more source
External radiotherapy of thyroid cancer [PDF]
, 2001 Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
core +1 more source
Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation. [PDF]
PLoS ONE, 2014 Thyroid hormone entry into cells is facilitated by transmembrane transporters. Mutations of the specific thyroid hormone transporter, MCT8 (Monocarboxylate Transporter 8, SLC16A2) cause an X-linked syndrome of profound neurological impairment and altered
Bárbara Núñez +8 more
doaj +1 more source
Hypothyroidism and nephrotic syndrome: why, when and how to treat [PDF]
, 2017 Hypothyroidism, characterised by low/normal free thyroxine (FT4) and free tri-iodothyronine (FT3) with elevated thyroid-stimulating hormone (TSH), is a well-known complication of nephrotic syndrome (NS).
Barbano, Biagio +7 more
core +1 more source
Middle East Fertility Society Journal, 2018 Background: Using anti_mullerian hormone (AMH) for Polycystic Ovary Syndrome diagnosis is not always constant. Thyroid dysfunction may effect on AMH levels.
Samal Hakeem Kareem AL-Jaff
doaj +1 more source
Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]
, 2013 Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc +6 more
core +1 more source
Thyroid hormone function in the rat testis
Frontiers in Endocrinology, 2014 Thyroid hormones are emerging regulators of testicular function since Sertoli, germ and Leydig cells are found to express thyroid hormone receptors. These testicular cells also express deiodinases which are capable of converting the pro-hormone T4 to the
Ying eGao, Will M. eLee, C Yan eCheng
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Nowadays, emerging evidence has shown adverse pregnancy outcomes, including preterm birth, preeclampsia, cesarean, and perinatal death, occurring in pregnant women after getting infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...
Qiman Shi +9 more
doaj +1 more source