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The Syndromes of Resistance to Thyroid Hormone Beta
罕见病研究, 2023 The syndrome of resistance to thyroid hormone(RTH) is a rare syndrome caused by the mutation of thyroid hormone receptor (TR) gene, which reduces the sensitivity of target organs to thyroid hormone (TH) and leads to the dysfunction of TH. Thyroid hormone
WANG Huangman +2 more
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Mechanism of thyroid-hormone regulated expression of the SERCA genes in skeletal muscle: Implications for thermogenesis [PDF]
, 2001 Thyroid hormone increases the Ca2+-ATPase activity of the sarcoplasmic reticulum (SR) in skeletal muscle, thereby increasing the energy-turnover associated with Ca2+-cycling during contraction and rest. The fast-muscle isoform of the Ca2+-ATPase (SERCA1)
Hardeveld, C. +9 more
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BMC Genomics, 2011 Background Disruption of thyroid hormone signalling can alter growth, development and energy metabolism. Thyroid hormones exert their effects through interactions with thyroid receptors that directly bind thyroid response elements and can alter ...
Paquette Martin A +6 more
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Thyroid hormone upregulates zinc-α2-glycoprotein production in the liver but not in adipose tissue. [PDF]
PLoS ONE, 2014 Overproduction of zinc-α2-glycoprotein by adipose tissue is crucial in accounting for the lipolysis occurring in cancer cachexia of certain malignant tumors.
Rafael Simó +5 more
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External radiotherapy of thyroid cancer [PDF]
, 2001 Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
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Effect of Antiepileptic Drug Treatment on Thyroid Hormone Levels in Epilepsy Patients
Haseki Tıp Bülteni, 2019 Aim:Antiepileptic drugs (AEDs) can have an effect on hormone metabolism and function, and alter serum levels of some hormones. This study aimed to determine the effects of AEDs on thyroid function test results in epilepsy patients.Methods:The study ...
Aytül Mutlu
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TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
Pickardt, C. R., Scriba, Peter Christian
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Role of maternal thyroid hormones in the developing neocortex and during human evolution
Frontiers in Neuroanatomy, 2013 The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
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Frontiers in EndocrinologyPurposeThis study aims to explore the association between impaired thyroid hormone sensitivity and hyperuricemia, and to analyze the potential mediating role of total cholesterol (TC), thereby providing a new theoretical basis for the early prevention ...
Xiying Huang, Xiying Huang, Daojun Yu
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Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]
, 2013 The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
Mohammed Elsalanty +19 more
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