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Thyroid Hormone Deiodination

Thyroid, 1990
A case is presented of Graves' disease occurring in a patient with hemiagenesis of the thyroid gland. The diagnosis was suspected clinically and was confirmed by laboratory tests and imaging studies, as well as by the presence of thyroid-stimulating antibody.
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Thyroid Hormones and Derivatives: Endogenous Thyroid Hormones and Their Targets

2018
More than a century after the discovery of L-Thyroxine, the main thyroid hormone secreted solely by the thyroid gland, several metabolites of this iodinated, tyrosine-derived ancestral hormone have been identified. These are utilized as hormones during development, differentiation, metamorphosis, and regulation of most biochemical reactions in ...
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Metabolism of the Thyroid Hormones

Hormone Research, 2008
This review covers the current knowledge about the various metabolic pathways involved in the conversion of thyroid hormones to the thyromimetically active and inactive iodothyronines. The concerted mechanism of systemic and local production of iodothyronines by tissue-specific iodothyronine deiodinase isozymes will ultimately determine the expression ...
J, Köhrle, G, Brabant, R D, Hesch
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Thyroid hormones and the heart

Hormone Molecular Biology and Clinical Investigation, 2014
Abstract Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormones deficit as well as excess are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics.
Hernando, Vargas-Uricoechea   +1 more
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Thyroid hormone and obesity

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
To review several of the most recent and most important clinical studies regarding the effects of thyroid treatments on weight change, associations between thyroid status and weight, and the effects of obesity and weight change on thyroid function.Weight decreases following treatment for hypothyroidism.
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Thyroid hormone and angiogenesis

Vascular Pharmacology, 2010
In models of thyroid hormone-induced cardiac hypertrophy, there is appropriate, supportive angiogenesis. Twenty years ago in one such model, angiogenesis in response to the hormone was observed before hypertrophy developed and it is now understood that iodothyronines induce neovascularization in a variety of settings, including the heart, ischemic ...
Mary K, Luidens   +4 more
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Radioimmunoassay of Thyroid Hormones

1987
The main role of the thyroid gland is to metabolize and to incorporate iodine into a variety of organic compounds, which include the metabolically active thyroid hormones, 3,5,3′,5′-tetraiodothyronine or thyroxine (T4) and 3,5,3′-triiodothyronine (T3), and several other precursors and degradation products, as summarized in Table 1 (for review see ...
Bartalena L   +2 more
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Thyroid Hormone and the Gut

Endocrine Research, 1988
The gastrointestinal tract interacts actively with the thyroid hormones, T4 and T3. Both T4 and T3 are absorbed well but incompletely from the gut, and many factors affect this absorption. The mechanism of absorption is unknown. It is decreased in most malabsorption conditions, but is increased in the postgastrojejunotomy syndrome.
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A New Perspective on Thyroid Hormones: Crosstalk with Reproductive Hormones in Females

International Journal of Molecular Sciences, 2022
Yan Zhu
exaly  

THE THYROID HORMONE

Journal of the American Medical Association, 1954
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