Results 111 to 120 of about 190,183 (351)

Coexistence of medullary thyroid carcinoma and recurrent non-functional pituitary adenoma: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Medullary thyroid carcinoma and pituitary adenoma are neuroendocrine tumors and their coexistence has not been reported in the literature, previously. Medullary thyroid carcinoma is a neoplasm of the thyroid gland arising from parafollicular c-
Mohammad Bagherzadeh   +3 more
doaj   +1 more source

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong   +3 more
wiley   +1 more source

Unusual cause of solitary pulmonary nodule

open access: yesSaudi Journal of Medicine and Medical Sciences, 2015
Papillary thyroid carcinoma is a common type of differentiated thyroid neoplasms with metastasis mostly described in the literature as occurring in the thyroid gland or in the surrounding cervical lymph nodes.
Yasser M Aljehani   +2 more
doaj   +1 more source

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

open access: yesAdvanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou   +27 more
wiley   +1 more source

Restored vision in a young dog following corticosteroid treatment of presumptive hypophysitis [PDF]

open access: yes, 2016
Background: Hypophysitis is an umbrella term for a group of disorders involving inflammation of the pituitary gland. A rare occurrence in humans, hypophysitis can produce a range of clinical signs including (but not limited to) visual deficits and ...
Liuti, Tiziana   +3 more
core   +2 more sources

Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation [PDF]

open access: bronze, 2012
Xiulong Xu   +8 more
openalex   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu   +8 more
wiley   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

open access: yes, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Colborn T   +13 more
core   +2 more sources

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