Results 51 to 60 of about 34,170 (239)

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

The effect of thyroid nodule location in ultrasound on the diagnosis of papillary thyroid carcinoma

Discover Oncology
Objective Exploring the role of nodule location in the diagnosis of papillary thyroid carcinoma in Chinese patients. Methods This study is a retrospective analysis of thyroid nodule patients who underwent surgery in our hospital from Jan 2022 to Dec 2023.
Jia-fei Hu, Jun Xu, Li-ping Gao, Xiao-lin Shen, Yan-li Wang, Min-juan Wu, Ling Zhang   +6 more
doaj   +1 more source

Thyroid Nodule Inspection as Consideration for Surgery

Scientiae Educatia: Jurnal Pendidikan Sains, 2018
Thyroid gland is essential in our body metabolism. Sometimes there are nodules on it, whether on palpation or unexpected finding from an ultrasound test. Based on thyroid function importance in metabolism, then not all thyroid nodule needs to be operated.
Yuliana Yuliana
doaj   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report

Radiology Case Reports
Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA.
Le Thi My, MD, Tran Thi Hoang Anh, MD, Nguyen Thi Thanh Hien, MD, Vu Mai Quynh, MD, Ngo Thi Thanh Tu, MD, Pham Vu Hiep, MD, Ngo Van Doan, PhD, Duong Manh Cuong, MD, Thieu Thi Tra My, MD   +8 more
doaj   +1 more source

Do TNF Inhibitors Increase the Frequency of Thyroid Nodules in Axial-spondyloarthritis Patients? A Case–control Study

Boğaziçi Tıp Dergisi, 2023
INTRODUCTION: Tumor necrosis factor (TNF) inhibitors have made great progress in the management of axial spondyloarthritis (axSpA). An increase in malignancies associated with TNF inhibitors has always raised suspicions but is unproven.
Esra Dilşat Bayrak, Ilknur Aktaş, Feyza Ünlü Özkan, Irem Buse Kurucu Zeytin, Kemal Sarı, Esin Derin Çiçek   +5 more
doaj   +1 more source

Predicting risk of malignancy in patients with indeterminate thyroid nodules [PDF]

, 2018
Thyroid cancer is the most prevalent endocrine cancer (1). The prevalence of palpable thyroid nodules in the general adult population is 4% to 7% (2). Ultrasound imaging detects thyroid nodules in 19%-68% of randomly selected individuals (3). The rate of
Carnes, Nicholas
core  

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Apropos of quality for fine-needle aspiration cytology of thyroid nodules with 22-, 23-, 25-, even 27-gauge needles and indeterminate cytology in thyroidology: an aide memory [PDF]

, 2022
İlker Şengül, Demet Şengül
openalex   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source