Results 111 to 120 of about 47,115 (244)

Clinical heterogeneity in vitiligo: Identification of clinical markers based patient clusters

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Vitiligo is a chronic autoimmune disease with heterogeneous clinical presentations. This study analysed 399 patients using hierarchical clustering and identified five phenotypes based on clinical characteristics and lesion distribution. Two groups exhibited high disease activity and extensive involvement.
Laura Galissi, Tristan Benoît, Ribal Merhi, Claire Drullion, Nicolas Andreu, Khaled Ezzedine, Thomas Darde, Katia Boniface, Julien Seneschal   +8 more
wiley   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection

International Journal of Endocrinology, 2014
Frequently, patients with hepatitis C virus (HCV) chronic infection have high levels of serum anti-thyroperoxidase and/or anti-thyroglobulin autoantibodies, ultrasonographic signs of chronic autoimmune thyroiditis, and subclinical hypothyroidism, in ...
Poupak Fallahi, Silvia Martina Ferrari, Ugo Politti, Dilia Giuggioli, Clodoveo Ferri, Alessandro Antonelli   +5 more
doaj   +1 more source

Association of candidate gene polymorphisms for autoimmune thyroid diseases in patients with familial diffuse toxic goiter and autoimmune thyroiditis

Клиническая и экспериментальная тиреоидология, 2016
Aim: to study the relation polymorphism of some genes of the immune response with familial autoimmune thyroid disease. Materials and methods. 100 patients from 49 families were examined.
Oksana D. Rymar, Anna K. Mikitinskaya, Vladimir N. Maksivov, Sergei G. Shahmatov, Yuliya V. Schepina, Andrew N. Ryabikov, Svetlana V. Mustafina   +6 more
doaj   +1 more source

Dermoscopy of Lichen Planus Follicularis Tumidus: A Case Report With Pattern Analysis and Literature Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Lichen planus follicularis tumidus (LPFT) is a rare variant of lichen planus presenting as erythematous to violaceous plaques with significant follicular involvement, most commonly in the retroauricular area. We report a case demonstrating a novel dermoscopic pattern reminiscent of a follicular galaxy, composed of variably sized comedo‐like ...
Vahidehsadat Azhari, Mina Saber
wiley   +1 more source

Retrospective analysis of cutaneous immune‐related adverse events following checkpoint inhibitor therapy in melanoma patients reveals increased risk associated with the HLA‐B*51:01 allele

Cancer, Volume 132, Issue 3, 1 February 2026.
ABSTRACT Background While immune checkpoint inhibitors (ICIs) have shown significant efficacy, a common side effect is cutaneous immune‐related adverse events (irAEs). This study focuses on exploring the association between specific human leukocyte antigen (HLA) alleles and the development of cutaneous irAEs in melanoma patients undergoing ICI ...
Mckenzie DiLeo, Samantha Oglesby, Cheuk Hong Leung, Kristen E. Pauken, Sahira Farooq, Lauren E. Haydu, Shelby L. Kubicki, Rebeca Martinez, Macartney Welborn, Sana Zahiruddin, Jun Zou, Kai Cao, Anisha B. Patel   +12 more
wiley   +1 more source

The Effect of Simvastatin on Thyroid Function in Experimental Autoimmune Thyroiditis Induced in Rats

Iraqi Journal of Pharmaceutical Sciences
Autoimmune thyroiditis or Hashimoto’s thyroiditis (HT): is the most common autoimmune thyroid disease. is characterized by marked lymphocytic infiltration and the presence of serum autoantibodies against Thyroid peroxidase (TPO) and Thyroglobulin (TG ...
Yaqeen Talib Mohammed, Nadia Hameed Mohameed , Inaam Samih Arif   +2 more
doaj   +1 more source

SREAT presenting as decades of intractable seizures and isolated delusional episodes with clinical, laboratory, and EEG confirmation of treatment response

SAGE Open Medical Case Reports, 2019
We report a case of a 60-year-old woman with a history of intractable seizures and isolated delusional psychosis who was later diagnosed with steroid-responsive encephalopathy associated with autoimmune thyroiditis.
Elysia Tjong, Rachael Gardner, Yen-Yi Peng   +2 more
doaj   +1 more source

Acute collapse in a dog with multiple autoimmune syndromes and polymyositis complicated by suspected organophosphate/carbamate toxicity

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer, Efrat Kelmer, Michal Mazaki Tovi, Dana Peery, Kobi Aharoni, Nir Edry, Sigal Klainbart   +6 more
wiley   +1 more source