Results 131 to 140 of about 47,115 (244)

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS Syndrome) Manifesting With Pseudolymphoma Multisystemic Organ Involvement

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Drug reaction with Eosinophilia and Systemic Symptoms is a rare significant cutaneous adverse reaction with associated mortality. Extensive pseudolymphomatous multiorgan manifestations with prolonged latency from nonsteroidal anti‐inflammatory exposure highlight the clinical spectrum and severity.
Hilary Regan, Gerard O. Sullivan, Pauline Marren   +2 more
wiley   +1 more source

Clinical features of spontaneous hypothyroidism in one physician’s practice in Jamaica

International Journal of General Medicine, 2010
Rosemarie A Wright-PascoeDepartment of Medicine, The University of the West Indies, Kingston, JamaicaObjective: To describe the clinical characteristics of patients with spontaneous hypothyroidism, the frequency of chronic autoimmune thyroiditis, and the
Rosemarie A Wright-Pascoe
doaj  

DiGeorge Syndrome Complicated by Secondary Antiphospholipid Syndrome Presenting With Vascular Thrombosis

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT DiGeorge syndrome (22q11.2 deletion syndrome) is a congenital disorder typically identified in infancy, but adult presentations may feature autoimmune and thrombotic complications. We report a 30‐year‐old woman with known DiGeorge syndrome who presented with progressive right lower extremity pain.
Aziz‐ur‐Rahman Khalid, Islam Rajab, Sakeena Saife, Anwar Zahran, Ghassan Makhoul, Hasan Munshi, Ibraheem Chaudhry, Robert Lahita   +7 more
wiley   +1 more source

Clinical Course and Risk Factors of Lenvatinib‐Related Hypothyroidism in Hepatocellular Carcinoma: A Retrospective Cohort Study

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Lenvatinib‐related hypothyroidism occurs in 16%–22% of patients with hepatocellular carcinoma and may affect treatment management. Previous studies have reported elevated serum thyroid stimulating hormone (TSH) levels despite levothyroxine therapy, indicating the need for research on the optimal levothyroxine dose during lenvatinib ...
Chihiro Shiraishi, Hideo Kato, Yuki Asai, Takuya Iwamoto   +3 more
wiley   +1 more source

Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly, Thomas Forst, Monika Kellerer, Stefanie Lanzinger, René D. Rötzer, Matthias Schott, Petra‐Maria Schumm‐Draeger   +6 more
wiley   +1 more source

Subdural Hematoma in Grave’s Disease Induced Thrombocytopenia. [PDF]

, 2013
Subdural hematoma (SDH) usually occurs secondary to trauma, in bleeding disorders it may occur spontaneously. It is a rare complication of immune thrombocytopenia.
Chandek, S, Diwan, S, Kakani, A, Kumar, S, Nitey, PO   +4 more
core   +1 more source

The Combined Effects of an Anti‐Inflammatory Diet and Curcumin Supplementation on Thyroid Function and Lipid Profile in Patients With Hashimoto's Thyroiditis: A Double Blind Randomised Clinical Trial

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Anti‐TPO levels, along with waist circumference and waist‐to‐hip ratio, showed notable reductions in the curcumin group compared to placebo, while other thyroid‐related and metabolic markers remained largely unchanged. ABSTRACT Background Hashimoto's thyroiditis (HT) is an inflammatory autoimmune disease and patients with HT may benefit from ...
Fatemeh Bourbour, Behnam Mahdavi, Niayesh Naghshi, Zahra Yari, Seyedsina Moghimnejad hosseini, Saeid Kalbasi, Golbon Sohrab   +6 more
wiley   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, Volume 48, Issue 1, Page 160-174, January 2026.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti, Joseph M. Curry, Jennifer Johnson, Michael Kwon, Shirley Y. Su, Francisco Civantos, Coral Olazagasti, Joseph Valentino, Susanne M. Arnold, R. Bryan Bell, Michael K. Gibson, Kyle Mannion, Kathryn M. Van Abel, Katharine A. Price, Haiying Dong, Amy H. Thorne, Toshiaki Suzuki, Ann M. Gillenwater   +17 more
wiley   +1 more source

Hodgkin Lymphoma With Liver Involvement (Diagnostic, Therapeutic Difficulties, and Literature Review): A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims In classical Hodgkin lymphoma liver involvement occurs in 5%–8%, ranging from mild dysfunction to acute liver failure. Recognition and treatment of advanced cases are challenging due to rapid progression and limited use of therapies. Methods We analyzed the data of 250 Hodgkin lymphoma patients; 9 had liver involvement, one
Fanni Borics, Roxana Szabó, Sándor Barna, Judit Bedekovics, Boglárka Brúgós, Árpád Illés, Zsófia Miltényi   +6 more
wiley   +1 more source