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Current Opinion in Rheumatology, 2012
Autoimmune thyroid disorders (AITDs) are the most common organ-specific autoimmune disorders. The genetics as well as clinical and laboratory manifestations of AITDs are reviewed.We discuss the association between specific rheumatologic disorders and AITDs and manifestations of AITDs that mimic rheumatologic disorders.
Nikolaos, Stathatos, Gilbert H, Daniels
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Autoimmune thyroid disorders (AITDs) are the most common organ-specific autoimmune disorders. The genetics as well as clinical and laboratory manifestations of AITDs are reviewed.We discuss the association between specific rheumatologic disorders and AITDs and manifestations of AITDs that mimic rheumatologic disorders.
Nikolaos, Stathatos, Gilbert H, Daniels
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Chronic Autoimmune Thyroiditis
New England Journal of Medicine, 1996In 1912, Hashimoto described four women in whom the thyroid gland was enlarged and appeared to have been transformed into lymphoid tissue (“struma lymphomatosa”).1 Although the patients were not initially hypothyroid, they became so after thyroid surgery.
C M, Dayan, G H, Daniels
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2014
Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
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Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
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Autoimmunity in Thyroid Disease
New England Journal of Medicine, 1959AUTOIMMUNE processes have been implicated in a variety of systemic disorders, including some primary hemolytic anemias, idiopathic thrombocytopenia, drug-induced neutropenias and collagenvascular diseases. The immunologic basis for such disorders has not been directly substantiated, and some investigators resist the concept that the body can develop ...
M J, CLINE, H A, SELENKOW, M S, BROOKE
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Development of thyroid autoimmunity
Acta Endocrinologica, 1985Abstract. Two blood samples were taken at an interval of 5 years in a continuing epidemiological study of a rural population in south-western Finland with an age range of 40–64 years at commencement. Paired sera of 680 subjects were tested for antibodies against thyroglobulin and thyroid microsomal antigen. In the seroconversion cases the titres in the
K, Aho, A, Gordin, T, Palosuo, J, Takala
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Annual Review of Medicine, 1986
The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
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The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
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Thyroid autoimmunity and aging
Experimental Gerontology, 1998Aging is associated with the appearance of several serum autoantibodies, including thyroid autoantibodies. The biological and clinical significance of this phenomenon is still unknown, because, with the exception of primary myxedema, the prevalence of clinically overt thyroid autoimmune diseases is not increased in the elderly.
MARIOTTI, STEFANO +3 more
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Seminars in Nuclear Medicine
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
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Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
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Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
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Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
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Thyroid Antigens and Autoimmunity
1971Publisher Summary This chapter discusses the autoantigens of the thyroid gland as well as the known proteins that seem to be characteristic of this organ. The important antigens can be understood on the basis of chemical analyses of their macromolecular nature.
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