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Thyroid Autoimmunity

2014
Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
openaire   +2 more sources

Impact of nutritional iodine optimization on rates of thyroid hypoechogenicity and autoimmune thyroiditis: a cross-sectional, comparative study.

Thyroid, 2015
BACKGROUND Since several countries have established mandatory food iodine fortification, there has been a decrease in rates of iodine deficiency disorders in parallel with an increase in prevalence of autoimmune thyroid diseases.
Daniela M C Miranda   +7 more
semanticscholar   +1 more source

Selenium and Iodine in Autoimmune Thyroiditis.

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2015
Selenium and iodine are essential for thyroid hormone synthesis and function. Selenium, in form of selenocysteine, is found either in the catalytic center of enzymes involved in the protection of the thyroid gland from free radicals originating during ...
E. Guastamacchia   +3 more
semanticscholar   +1 more source

Autoimmune thyroiditis and ROS

Autoimmunity Reviews, 2008
Autoimmune thyroiditis, also known as chronic lymphocytic or Hashimoto's thyroiditis, is characterized by infiltration of the thyroid gland by inflammatory cells and production of autoantibodies to thyroid-specific antigens thyroglobulin and thyroperoxidase.
Noel R. Rose, C. Lynne Burek
openaire   +3 more sources

Juvenile Autoimmune Thyroiditis

Journal of Pediatric Endocrinology and Metabolism, 2007
Autoimmune thyroiditis is a frequent cause of goiter in children and studies point to the increasing prevalence of juvenile autoimmune thyroiditis (JAT) in children and adolescents. Clinically, JAT can manifest, depending on the presence or absence of goiter, as either a goitrous form or atrophic form.
Raman K. Marwaha   +1 more
openaire   +3 more sources

Autoimmune Thyroid Disease

Clinics in Laboratory Medicine, 1993
A considerable proportion of the thyroid diseases is due to aberrant immune reactions toward thyroid antigens. Autoreactivity is considered to be a normal process controlled by several suppressor mechanisms. Malfunction of these suppressor mechanisms may result in autoimmune disease.
P. Mooij, H.A. Drexhage
openaire   +3 more sources

Stress and Thyroid Autoimmunity

Thyroid, 2004
While many studies have shown a connection between stress and autoimmune disease, most of the evidence for stress contributing to the onset and course of autoimmune disease is circumstantial and the mechanisms by which stress affects autoimmune disease are not fully understood.
Audrey W. Li   +3 more
openaire   +3 more sources

Development of thyroid autoimmunity

Acta Endocrinologica, 1985
Abstract. Two blood samples were taken at an interval of 5 years in a continuing epidemiological study of a rural population in south-western Finland with an age range of 40–64 years at commencement. Paired sera of 680 subjects were tested for antibodies against thyroglobulin and thyroid microsomal antigen. In the seroconversion cases the titres in the
J Takala, K Aho, A. Gordin, T. Palosuo
openaire   +3 more sources

CHRONIC THYROIDITIS AND AUTOIMMUNIZATION

Journal of the American Medical Association, 1957
• An explanation of chronic thyroiditis in man was sought in observations made on rabbits, dogs, guinea pigs, and human subjects. The rabbits received injections of saline extracts of rabbit thyroid glands. The tests for circulating autoantibodies utilized the phenomena of precipitation, complement fixation, and tanned-cell hemagglutination.
Noel R. Rose   +4 more
openaire   +3 more sources

Autoimmune thyroid diseases

Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Hiroaki Kimura   +3 more
openaire   +2 more sources

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