Results 11 to 20 of about 52,369 (184)
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
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BMJ, 1973 Four patients are described who were surreptitiously taking thyroxine-containing tablets. In two cases this caused considerable diagnostic problems. The diagnosis should be considered in patients with clinical features of hyperthyroidism (but without goitres or proptosis), who appear psychiatrically abnormal and whose thyroid function tests show ...
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
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Experimental Biology and Medicine, 1951 SummaryFollowing injection of I131 labeled L-thyroxine into intact and thyroid-ectomized mice and intact rats, tissues and excreta were investigated by radioautography of paper chromatograms of their butanol extracts. Four substances, namely thyroxine, iodide and two unidentified iodine containing substances referred to as compounds Nos.
J, GROSS, C P, LEBLOND
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Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
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Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
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Medication counseling for thyroxine
Indian Journal of Endocrinology and Metabolism, 2017 This communication from the National Indian Patient-centered Thyroid Management group provides a useful tool to help in medication counseling during hypothyroidism management. The authors classify and list aspects of thyroxine use which must be discussed with patients on thyroxine supplementation or replacement.
Sanjay Kalra +14 more
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Advanced Science, EarlyView.After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang +19 more
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Cardiovascular Effects of Thyroxine
Cardiovascular Research, 1969 The chronic administration of relatively small doses of thyroxine to cats and guinea-pigs gave rise to an increased excitability of the heart associated with an increased sensitivity to vagal stimulation, an increased mitochondrial respiration and phosphorylation, and an increase in mitochondrial mass.
Zaimis, E. +6 more
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Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
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