Results 41 to 50 of about 135,065 (327)

Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy [PDF]

open access: yes, 2010
Hepatic haemiangiomas in infancy are rare. An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 ...
Catherine Peters   +7 more
core   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Association between thyroid cancer and cardiovascular disease: A meta-analysis

open access: yesFrontiers in Cardiovascular Medicine, 2023
ObjectiveTo determine the association between thyroid cancer and coronary artery disease, atrial fibrillation, cerebrovascular disease, and cardiovascular disease mortality.MethodsThe PubMed, Embase, and Cochrane Library databases were searched for ...
Wen-Hsuan Tsai   +14 more
doaj   +1 more source

Medication counseling for thyroxine

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
This communication from the National Indian Patient-centered Thyroid Management group provides a useful tool to help in medication counseling during hypothyroidism management. The authors classify and list aspects of thyroxine use which must be discussed with patients on thyroxine supplementation or replacement.
Sanjay Kalra   +14 more
openaire   +3 more sources

Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]

open access: yes, 2013
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core  

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

Effect of certain thyroxine analogues on liver cholesterol

open access: yes, 1960
l-Thyroxine, l-triiodothyronine, their d-isomers, and their formic, acetic, propionic and butyric acid analogues were given to cholesterol-thiouracil-fed rats and the effect on thyroid weight and serum and liver cholesterol determined.
Charles H. Duncan, Maurice M. Best
core   +1 more source

SLC25A4high Hepatocytes Enhance Lifestyle Intervention Response in MASLD by Recruiting Eating Macrophages

open access: yesAdvanced Science, EarlyView.
SLC25A4high hepatocytes drive metabolic‐associated steatotic liver disease (MASLD) remission by recruiting lipid‐eating macrophages. The hepatocyte Slc25a4/PANX1/ATP/P2ry12 axis mediates find‐me signaling that triggers macrophage recruitment and efferocytosis, while recruited macrophages secrete GDF15 to activate hepatocyte PPARα and promote fatty acid
Yiting Qian   +8 more
wiley   +1 more source

Dyslipidemia in subclinical hypothyroidism and the effect of thyroxine on lipid profile

open access: yesIndian journal of endocrinology and metabolism, 2012
Introduction: Subclinical hypothyroidism (SH) has a prevalence between 4% and 10.5% in various studies. The burden of SH in India is expected to increase with increasing iodine sufficiency.
A. Asranna, R. Taneja, Bindu Kulshreshta
semanticscholar   +1 more source

Antithyroxine effects of some thyroxine analogues

open access: yes, 1959
Several diiodo- and triiodothyronines and their propionic and acetic acid analogues were evaluated for thyroxine-antagonizing capacity. The postabsorptive metabolic rate of thyroidectomized rats maintained on 20 µg L-thyroxine/ kg/day was used as the ...
Constance S. Pittman, S. B. Barker
core   +1 more source

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