Results 61 to 70 of about 50,875 (176)

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, Volume 104, Issue 4, Page 372-385, April 2026.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Sequential Amiodarone‐Induced Thyroid Dysfunction: From Myxedema Coma to Late‐Onset Type 1 Thyrotoxicosis After Drug Withdrawal

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Amiodarone therapy may induce thyroid dysfunction in approximately 20% of patients, either amiodarone‐induced hypothyroidism (AIH) or thyrotoxicosis (AIT). Both situations may occur at any time during treatment or even months to years after drug withdrawal due to tissue storage with slow systemic release.
Daniela M. Soares, Lia Ferreira
wiley   +1 more source

Case Report of Acute Severe Hyponatremia Induced by Desmopressin Administration During Chemotherapy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Patients undergoing chemotherapy are prone to developing hyponatremia due to insufficient oral intake because of nausea and vomiting, administration of large volumes of intravenous fluids, syndrome of inappropriate antidiuretic hormone secretion induced by chemotherapeutic agents, adrenal insufficiency, and drug interactions.
Koutaro Ono, Shugo Uematsu, Aya Yoshihara, Ayako Tsuboya, Shoichi Mori, Takashi Yoshioka, Shuichi Nawata   +6 more
wiley   +1 more source

Severe Headache and Acute Blindness: A Case of Pituitary Apoplexy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Pituitary apoplexy is a rare, life‐threatening syndrome that commonly occurs in the adenomatous pituitary gland. It presents with a myriad of severe neuroendocrine and ophthalmological signs and symptoms. Early diagnosis and prompt treatment are vital in the management of pituitary apoplexy.
Abdul‐Rahman Faiza, Adwoa Agyemang Adu‐Gyamfi, Kwaku Asare‐Ankomah, Kwadwo Faka Gyan, Solomon Gyabaah   +4 more
wiley   +1 more source

Subacute Thyroiditis Without Neck Pain: An Unusual Cause of Persistent Fever in the Elderly Patient

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Subacute thyroiditis can present as fever of unknown origin, particularly in elderly patients. Absence of neck pain or thyroid tenderness does not exclude the diagnosis. Thyroid function tests and inflammatory markers are key to diagnosis. Corticosteroids lead to rapid symptomatic improvement in moderate‐to‐severe cases.
Abdullah Shahid, Aasim Ali, Javed Iqbal, Muhammad Asad Shabbir, Usama Saleem, Muhammad Shahzeb, Danish Yousuf, Gohar Mushtaq, Armaghana Abdullah, Mukesh Kumar Sharma   +9 more
wiley   +1 more source

Peripheral Neuropathy Induced by a Short Course of Metronidazole: A Case Report of Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Metronidazole is a commonly used antibiotic with a good safety and economic profile, but it may rarely be neurotoxic, causing peripheral neuropathy and encephalopathy. Most literature suggests that prolonged drug therapy, that is, a duration of > 4 weeks and a dosage of > 42 g, is associated with neurotoxicity, though the exact dose‐dependent ...
Sonam Dhenga, Milan Pokhrel, Simran Rauniyar, Kundan Kumar Yadav, Sony K.C., Sugam Ale Magar   +5 more
wiley   +1 more source

Associations of Multimarkers of Metabolic Malnutrition and Inflammation With All‐Cause Mortality and Their Interplay With Thyroid Function

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
MVX, Thyroid Function and Mortality. ABSTRACT Introduction The metabolic vulnerability index (MVX)—a composite biomarker reflecting metabolic malnutrition and inflammation—has been linked to increased mortality risk in populations with cardiovascular disease.
Setor K. Kunutsor, Reyhaneh Rikhtehgaran, Yanning Xu, Margery A. Connelly, Irina Shalaurova, Layal Chaker, Stephan J. L. Bakker, Robin P. F. Dullaart   +7 more
wiley   +1 more source