Results 61 to 70 of about 4,397 (276)

Clasificación TI-RADS de los nódulos tiroideos en base a una escala de puntuación modificada con respecto a los criterios ecográficos de malignidad

open access: yesRevista Argentina de Radiología, 2014
Objetivo: El sistema de catalogación de los nódulos tiroideos (NT) TI-RADS (Thyroid Imaging Reporting and Data System), propuesto por Horvath et al. en 2009, se utiliza poco. El objetivo de este estudio fue evaluar una modificación en la escala de puntos
J. Fernández Sánchez
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Conventional ultrasound, color Doppler, TI-RADS, and shear wave elastography for thyroid nodule differentiation: a study of efficacy compared with the histopathology results

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2021
Background Although a minority of the thyroid nodules is malignant, usually the invasive diagnostic procedures are warranted. This prospective study aims to assess the diagnostic performance of the US criteria in addition to the TI-RADS score and the SWE
Ahmed Abd Alrahman Baz   +3 more
doaj   +1 more source

Radiomics Score Combined with ACR TI-RADS in Discriminating Benign and Malignant Thyroid Nodules Based on Ultrasound Images: A Retrospective Study

open access: yesDiagnostics, 2021
This study aimed to explore the ability of combination model of ultrasound radiomics score (Rad-score) and the thyroid imaging, reporting and data system by the American College of Radiology (ACR TI-RADS) in predicting benign and malignant thyroid ...
Peng Luo   +7 more
doaj   +1 more source

High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS

open access: yesCancer Management and Research, 2021
Thyroid cancer is the most common primary malignant disorder of the thyroid. We aimed to illustrate the modified TI-RADS report system for differentiating malignant thyroid nodules from benign ones, and especially its role in the management of high risk nodules.In this retrospective study, 5,162 healthy individuals who underwent thyroid ultrasound ...
Menghui Li   +6 more
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Is thyroid imaging reporting and data system useful as an adult ultrasonographic malignancy risk stratification method in pediatric thyroid nodules?

open access: yesJournal of Medical Ultrasound, 2019
Background: Data on thyroid imaging reporting and data system (TI-RADS) generally belong to studies performed in adults. Therefore, we aimed to evaluate the performance and utility of TI-RADS in the pediatric group.
Yasemin Durum Polat   +4 more
doaj   +1 more source

Impacto do uso do American College Of Radiology Thyroid Imaging Reporting And Data System (ACR TI-RADS) no desempenho das punções aspirativas com agulha fina de nódulos de tireoide [PDF]

open access: yes, 2020
Nódulos de tireoide são uma condição clínica prevalente, principalmente na população feminina. Nas últimas décadas, em função do avanço e maior disponibilidade dos métodos de imagem, houve um aumento da incidência de nódulos tireoidianos, na maioria dos ...
Strieder, Débora Lunkes
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Diagnostic accuracy of TI-RADS classification in differentiating benign and malignant thyroid nodules-a study from Southern Punjab, Pakistan

open access: yesBioMedica, 2021
Background and Objective: Thyroid imaging reporting and data system (TI-RADS) is developed to determine the risk of malignancy in patients with thyroid nodules.
Sumera Nighat   +5 more
doaj   +1 more source

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