Results 241 to 250 of about 1,691,962 (389)

The Design and Optimization of the Tie Rod to Ensure the Precision of the Cryogenicc Container in the 7 T MRI System

open access: green
Xu Zhao   +13 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

Image 4_VE-PTP controls a fluid shear stress set point that governs cell morphological responses through Tie-2.tiff

open access: green
Keisuke Shirakura (21246339)   +3 more
openalex   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Dual‐Array Nano Configuration for High‐Performance Metastable β Titanium Alloys

open access: yesAdvanced Science, EarlyView.
This work resolves a fundamental paradox in metastable alloys by establishing a novel dislocation‐phase coupling mechanism, enabling dynamic microstructure control for simultaneous thermal stability and deformability. Geometrically ordered α‐nanograins achieve unprecedented 500°C strength‐ductility synergy (863 MPa UTS, 78.3% elongation).
Tianle Li   +10 more
wiley   +1 more source

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

open access: yesAdvanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen   +16 more
wiley   +1 more source

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