Results 131 to 140 of about 82,650 (256)

Tibia, Diaphysis

open access: yes, 2014
Fractures of the tibia are brought on by a variety of high-energy injury mechanisms and are prone to complications. The lack of a circumferential soft tissue envelope around the bone makes the bone ends more likely to fail to unite.
Rami Mosheiff   +3 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

open access: yesAdvanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang   +10 more
wiley   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

La tibia y sus deformidades congénitas [PDF]

open access: yes, 1955
El presente estudio sobre la Tibia y sus anomalías congénitas lo hemos dividido en 2 grandes capítulos. En el primero bosquejamos sintéticamente los caracteres anatómicos y radiológicos del hueso tibial sano.
Malagón Castro, Valentín   +1 more
core  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

open access: yesAdvanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park   +13 more
wiley   +1 more source

Challenges of using tibia bone ash and toe ash as biomarkers of phosphorus nutrition for meat chickens [PDF]

open access: yes
Two experiments were conducted to determine the suitability of tibia bone ash and toe ash as biomarkers of phosphorus (P) status of broilers from day 1 to 21 (Experiment 1) and from day 21 to 49 (Experiment 2).
Zhang, D.   +5 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Right and left tibia.

open access: yes, 2013
Right tibia in: lateral (A & B); cranial (C & D); caudal (E & F); and medial (G & H) views; close up of fibular flange with fossa (I), right tibia in: proximal (J & K); and distal (L & M) views. Left tibia in: lateral (N); cranial
George H. K. Sinapius (155398)   +10 more
core   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

open access: yesAdvanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang   +18 more
wiley   +1 more source

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