Results 111 to 120 of about 82,650 (256)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Tunnel combinations that should be avoided in anterior cruciate ligament reconstruction: a biomechanical assessment of 15 different combinations of femoral and tibial graft tunnels

Bone & Joint Open
Aims: Structured knowledge on the combined effect of various positions of femoral and tibial tunnels in reconstruction of the anterior cruciate ligament (ACL) on knee range of motion, rotatory stability, and anterior translatory laxity is limited.
Salameh Eljaja, Jørgen Tranum-Jensen, Mette Tavlo, Volkert Siersma, Michael Rindom Krogsgaard   +4 more
doaj   +1 more source

MORPHOMETRIC FEATURES OF THE PROXIMAL TIBIA IN TURKISH SOCIETY AND ITS CLINICAL SIGNIFICANCE [PDF]

, 2016
Amaç: Çalışmamızın amacı tibia proksimal kısmının antropometrik ve morfometrik özelliklerinin belirlenmesi ve bu özelliklerin diğer toplumlarla karşılaştırılmasıdır.
Cemil Bilkay, Bilkay, Cemil, Öztürk, Kenan, Özgüner, Gülnur, Candan, Büşra, Dursun, Ahmet, Sulak, Osman, Kenan Öztürk, Büşra Candan, Osman Sulak, Ahmet Dursun, Gülnur Özgüner   +11 more
core  

Foot accelerations are larger than tibia accelerations during sprinting when measured with inertial measurement units

, 2019
Accelerometers are often placed on the tibia to measure segmental accelerations, and external mechanical load during running. However, in applied sport settings it is sometimes preferable to place accelerometers on the dorsal foot to avoid tibial impact ...
Alderson, Jacqueline A, Fuller, Joel T, Glassbrook, Daniel, Glassbrook, Daniel J, Fuller, Joel T., Doyle, Tim LA, Doyle, Tim L. A., Alderson, Jacqueline A.   +7 more
core   +1 more source

Functional and radiological outcome of expert tibia nailing in proximal tibia fractures [PDF]

, 2018
Background: Previously treatment of choice for proximal tibia fracture was internal fixation by plate. Presently, expert tibia nail is widely used in treating proximal tibia fracture.
Dagar, Preetam Singh, Pestonji, Jehangir Malcom, Chaallani, Abhay, Jadhav, Ashutosh Ajit, Kadam, Rahul   +4 more
core   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Diseño concurrente y proceso de fabricación de placas de bloqueo para diáfisis de fémur y tibia y tibia distal

, 2018
Hoy día en Venezuela existe una considerable demanda de elementos de osteosíntesis para el tratamiento de las fracturas, debido al alto índice de accidentes, tales como accidentes de tránsito y laborales. Además, cabe mencionar que estos dispositivos son
Lara M., Daniel O., Segatto G., Angelo S.   +1 more
core   +1 more source

Biomechanical and Injury Tolerance Analysis of Tibial Movement Under Different Postures and Impact Loads

Applied Sciences
The lower limbs play an important role in daily human activities. Therefore, a 3D tibial model is constructed, and finite element analysis is performed to investigate the biomechanical characteristics and injury tolerance of lower limb flexion movement ...
Lei Liu, Qian Qian, Hengjia Liu, Hongyan Liu, Jong-Chul Park   +4 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Sex Estimation from the Fibula and Tibia: A Study in Three Portuguese Reference Collections

Forensic Sciences
Background/Objectives: Sex estimation constitutes an important tool in the process of identifying an anonymous individual in forensic contexts. The bones commonly used in sex estimation are those that exhibit greater sexual dimorphism, such as the pelvis
Sandra Marques, Catarina Pinto, Maria Teresa Ferreira, Susana Garcia, Francisco Curate   +4 more
doaj   +1 more source