Results 101 to 110 of about 73,166 (264)

pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women

, 2013
In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern.
Rittweger, Jörn, Mortarino, Pablo, Feldman, Sara, Reina, P. S., Cointry, Gustavo, Capozza, R. F., Nocciolino, L. M., Ferretti, José Luis   +7 more
core  

Tibia, Diaphysis

, 2014
Fractures of the tibia are brought on by a variety of high-energy injury mechanisms and are prone to complications. The lack of a circumferential soft tissue envelope around the bone makes the bone ends more likely to fail to unite.
Rami Mosheiff, Frankie Leung, Mosheiff, R, Leung, FKL   +3 more
core   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Tunnel combinations that should be avoided in anterior cruciate ligament reconstruction: a biomechanical assessment of 15 different combinations of femoral and tibial graft tunnels

Bone & Joint Open
Aims: Structured knowledge on the combined effect of various positions of femoral and tibial tunnels in reconstruction of the anterior cruciate ligament (ACL) on knee range of motion, rotatory stability, and anterior translatory laxity is limited.
Salameh Eljaja, Jørgen Tranum-Jensen, Mette Tavlo, Volkert Siersma, Michael Rindom Krogsgaard   +4 more
doaj   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

Biomechanical and Injury Tolerance Analysis of Tibial Movement Under Different Postures and Impact Loads

Applied Sciences
The lower limbs play an important role in daily human activities. Therefore, a 3D tibial model is constructed, and finite element analysis is performed to investigate the biomechanical characteristics and injury tolerance of lower limb flexion movement ...
Lei Liu, Qian Qian, Hengjia Liu, Hongyan Liu, Jong-Chul Park   +4 more
doaj   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Sex Estimation from the Fibula and Tibia: A Study in Three Portuguese Reference Collections

Forensic Sciences
Background/Objectives: Sex estimation constitutes an important tool in the process of identifying an anonymous individual in forensic contexts. The bones commonly used in sex estimation are those that exhibit greater sexual dimorphism, such as the pelvis
Sandra Marques, Catarina Pinto, Maria Teresa Ferreira, Susana Garcia, Francisco Curate   +4 more
doaj   +1 more source

La tibia y sus deformidades congénitas [PDF]

, 1955
El presente estudio sobre la Tibia y sus anomalías congénitas lo hemos dividido en 2 grandes capítulos. En el primero bosquejamos sintéticamente los caracteres anatómicos y radiológicos del hueso tibial sano.
Malagón Castro, Valentín, Valentín Malagón Castro   +1 more
core  

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source