Results 141 to 150 of about 145,602 (269)

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Diagnosis and treatment of juvenile yellow granuloma in a child: A case report. [PDF]

Medicine (Baltimore)
Zhu J, Li Q, Dong Y.
europepmc   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Latarjet Procedure With Distal Tibia Allograft Augmentation for Anterior Shoulder Instability in a Convulsive Patient: A Case Report. [PDF]

Case Rep Orthop
Lima EBS, Paroneto AC, Vasconcelos GFS, Berto L, Lara PHS, Belangero PS, Pochini AC, Ejnisman B, Andreoli CV.   +8 more
europepmc   +1 more source

Determination of sex from the tibia in a contemporary Sri Lankan population

, 2019
Deepthi Nanayakkara, AmalNishantha Vadysinghe, Lakshika S. Nawarathna, Harshana Sampath   +3 more
openalex   +1 more source

Calcanisation of tibia using Ilizarov fixator in crush injuries of hindfoot: a new method [PDF]

, 2007
Mussa Wardak, Emal Wardak, Akshay Goel
openalex   +1 more source

Morphological and biomechanical effects of vitamin K2 on fracture healing: An animal study on the rat tibia fracture model

, 2023
Ömer Kays Ünal, Mirza Zafer DAĞTAŞ, Belkız Öngen İpek, Mustafa Erinç Sitar, Ender Uğutmen   +4 more
openalex   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Proximal tibial tuberculous osteomyelitis with secondary knee joint arthritis: A case report. [PDF]

Radiol Case Rep
Haichour I, Benalia K, Abdeljaouad N, Yacoubi H.   +3 more
europepmc   +1 more source

Locking Compression Plate for Distal Tibia Fractures

, 2016
Günther Theisz, Karel Frydrýšek, František Fojtík, Luboš Pečenka, Tomáš Kubín, Marek Sadílek, Jiří Kratochvíl, Jiří Demel, Roman Madeja, Leopold Pleva   +9 more
openalex   +1 more source