Results 41 to 50 of about 73,166 (264)

Tibia Pathology and Fractures [PDF]

open access: yes, 2020
The tibia is the larger, stronger, and anterior (frontal) of the two bones in the leg, which connects the knee with the ankle bones. The tibia, or shinbone, is the most fractured long bone in the body.

core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Osteofibrous Dysplasia Involving Both Tibia and Fibula: A Rare Campanacci-Type Presentation

open access: yesJournal of the Belgian Society of Radiology
Teaching point: Osteofibrous dysplasia (OFD) is a rare benign fibro‑osseous lesion primarily affecting the tibial cortex in children and adolescents; simultaneous involvement of the fibula is exceptional and may mimic more aggressive tumors such as ...
Caroline Chabot, Daniel Janssens
doaj   +1 more source

Lower Limb Malrotation following Minimally Invasive Plating in Distal Tibia Fractures [PDF]

open access: yes
Introduction: Minimally invasive percutaneous osteosynthesis (MIPO) plating techniques have demonstrated good outcomes in the treatment of distal tibia fractures. Early arthritis and functional impairment may occur if length and rotation are not restored.
Lee MJJR, Yap WMQ, Kwek EBK, Ng JW
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Case Report: 3D-Printed Prosthesis for Limb Salvage and Joint Preservation After Tibial Sarcoma Resection

open access: yesFrontiers in Surgery, 2022
IntroductionReconstruction of massive tibial defects in ankle joint-preserving surgery remains challenging though biological and prosthetic methods have been attempted.
Zehao Guo   +5 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez   +6 more
wiley   +1 more source

Anatomy of the Medial Meniscotibial Ligament of the Knee: A Systematic Review

open access: yesRevista Brasileira de Ortopedia, 2023
Objectives To perform a systematic review of the literature on the anatomy of the medial meniscotibial ligaments (MTLs), and to present the most accepted findings, as well as the evolution of the anatomical knowledge on this structure.
Jonatas Brito de Alencar Neto   +5 more
doaj   +2 more sources

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