Results 41 to 50 of about 32,296 (266)
Advanced Science, EarlyView.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
Double-Row Fixation for Avulsion of Anterior Cruciate Ligament
Arthroscopy Techniques, 2019 Avulsion fractures of the tibial spine (also called “tibial eminence fractures” or “ACL avulsion fractures”), leading to discontinuity of anterior cruciate ligament (ACL) fibers, have been well described in the literature in both the pediatric and adult ...
Ziyad Elqirem, M.D. +2 more
doaj +1 more source
Advanced Science, EarlyView.This work develops a soft hybrid electronic system with printed thermoresponsive hydrogel electrodes, which enables high‐fidelity neural signal acquisition and stimulation. The system precisely assesses median and ulnar nerve injuries in clinical cases, realizing accurate diagnosis of neural impairment while ensuring customized adhesion regulation ...
Bo Pang +13 more
wiley +1 more source
Orthopaedic SurgeryObjective The incidence of anterior cruciate ligament (ACL) ruptures has been increasing annually. However, clinical surgeons have overlooked the impaction fractures of the posterolateral tibial plateau and lateral femoral condyle in patients with ACL ...
Shijie Jiang +8 more
doaj +1 more source
High Incidence of Soft Tissue Injury in Pediatric Proximal Tibia Fractures: A Systematic Review
Arthroscopy, Sports Medicine, and Rehabilitation, 2023 Purpose: The purpose of this study was to describe the incidence of soft tissue injuries associated with pediatric proximal tibial fractures (PPTF) and the frequency that magnetic resonance imaging (MRI) was used before surgery in this patient population.
Ethan Sanders, M.D. +2 more
doaj +1 more source
Advanced Science, EarlyView.This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Advanced Science, EarlyView.Mechanical intelligence reframes bone regeneration as a time‐dependent coupling between material and cellular memory. Biomaterials store and release mechanical history, while cells retain prior cues and remodel the repair niche. Matching these memories to healing stages may guide stage‐specific scaffolds, sensing‐assisted prediction, mechanical dosing,
Jin Tian +8 more
wiley +1 more source
Advanced Science, EarlyView.A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang +14 more
wiley +1 more source
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Advanced Science, EarlyView.Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source
Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods
Advanced NanoBiomed Research, EarlyView.Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria +5 more
wiley +1 more source