Results 41 to 50 of about 61,744 (311)

External fixation in Schatzker J´s type VI tibial plateau fracture

Archivo Médico de Camagüey, 2020
Background: tibial plateau fractures are common traumatic lesions due to vertical compression in varus and valgus. That is why open fractures associated to skin loss are not so frequent, because they are caused by direct mechanisms. Objective: to show a
Alejandro Alvarez-López, Rodrigo Fuentes-Véjar, Sergio Ricardo Soto-Carrasco, Yenima de la Caridad García-Lorenzo   +3 more
doaj  

Chronic Bilateral Tibial Stress Fractures with Valgus Treated with Bilateral Intramedullary Nailing: A Case Report

Journal of Orthopaedic Case Reports, 2014
Introduction: Stress fractures are overuse injuries most commonly seen in athletes, military recruits, and individuals with endocrine abnormalities.
Steven K Dailey, Michael T. Archdeacon
doaj   +1 more source

6'-Methoxy Raloxifene-analog enhances mouse bone properties with reduced estrogen receptor binding [PDF]

, 2020
Raloxifene (RAL) is an FDA-approved drug used to treat osteoporosis in postmenopausal women. RAL suppresses bone loss primarily through its role as a selective estrogen receptor modulator (SERM).
Allen, Matthew R., Berman, Alycia G., Brown, Alexa P., Deosthale, Padmini, Plotkin, Lilian I., Powell, Katherine M., Pulliam, Alexis N., Skaggs, Cayla G., Wallace, Joseph M., Williams, David R.   +9 more
core   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Classification and Treatment Strategies of Tibial Tubercle Fractures in Adults

Orthopaedic Surgery
Objectives Tibial tubercle is a crucial player in maintaining the structural integrity and functional stability of the knee joint. Currently, there is no standardized protocol for the classification and treatment of tibial tubercle fractures in adults ...
Xiang Yao, Hongyuan Liu, Yuxuan Ma, Minjie Hu, Chong Wang, Han Miao, ShengJie Liu, Jilei Tang   +7 more
doaj   +1 more source

Impaction fractures of the anterior tibial plafond

OTA International, 2020
. Objectives:. To determine whether patients with AO/OTA 43-B anterior impaction tibial plafond fractures have worse clinical outcomes, and an increased risk of progression to ankle arthrodesis. Design:. Retrospective cohort study. Setting:.
Moaz B.Y. Chohan, MBBS, Christopher Del Balso, MBBS, MSc, FRCSC, Michael Ching, MD, Emil Schemitsch, MD, FRCSC, Abdel Rahman Lawendy, MD, PhD, FRCSC, David W. Sanders, MD, MSc, FRCSC   +5 more
doaj   +1 more source

Evaluation of Tibial Condyle Fractures Treated with Ilizarov Fixation, A Prospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Tibial plateau fractures are associated with significant soft tissue injuries which increases the risks of complications and must be considered when managing tibial plateau fractures.
Sandeep Reddy R, Yashavantha Kumar C, Harshad M Shah, Dinesh Kumar Golla, Niranthara Ganesh D J, Ashok Kumar P   +5 more
doaj   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

A Review of Tibial Shaft Fracture Fixation Methods

Trauma Care, 2023
Tibial shaft fractures are a commonly seen injury in orthopedic trauma patients. Fractures commonly occur following high energy mechanisms, such as motor vehicle collisions. There are multiple ways to stabilize tibial shaft fractures.
Lisa Tamburini, Francine Zeng, Dillon Neumann, Casey Jackson, Michael Mancini, Andrew Block, Seema Patel, Ian Wellington, David Stroh   +8 more
doaj   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

Advanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang, Yijin Hou, Likun Cui, Huiqi Yu, Rong Liu, Junhao Sui, Zhong Zheng, Lu Liu, Jie Chen, Mengchen Chen, Chen Ding, Shuogui Xu, Sheng Xu, Hao Zhang   +13 more
wiley   +1 more source