Results 51 to 60 of about 315,798 (254)

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

Evaluation of Tibial Condyle Fractures Treated with Ilizarov Fixation, A Prospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Tibial plateau fractures are associated with significant soft tissue injuries which increases the risks of complications and must be considered when managing tibial plateau fractures.
Sandeep Reddy R, Yashavantha Kumar C, Harshad M Shah, Dinesh Kumar Golla, Niranthara Ganesh D J, Ashok Kumar P   +5 more
doaj   +1 more source

ES OF THE TIBIAL PLATEAU: THE ROLE OF ARTHROSCOPIC ASSISTANCE

, 2018
We present our experience in the treatment of fractures of the tibial plateau with arthroscopic assistance. Between January 1997 and September 2001, we evaluated 23 patients with fractures of the tibial plateau.
Luca Khalil El Jaouni
core   +1 more source

Development and validation of a paediatric long-bone fracture classification : a prospective multicentre study in 13 European paediatric trauma centres [PDF]

, 2011
Background: The aim of this study was to develop a child-specific classification system for long bone fractures and to examine its reliability and validity on the basis of a prospective multicentre study.
Marzi, Ingo, Ralf Kraus, Lutz von Laer, Kraus, Ralf, Kaiser, Martin, Röder Christoph, von Laer Lutz, Schneidmüller, Dorien, Martin Kaiser, Dietrich, Daniel, Christoph Röder, Dietrich, Daniel J., Ingo Marzi, Kaiser Martin, Marzi Ingo, Röder, Christoph, Schneidmüller Dorien, Dietrich Daniel, von Laer, Lutz, Laer, Lutz von, Kraus Ralf, Dorien Schneidmüller, Daniel Dietrich   +22 more
core   +3 more sources

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

High Detection Rate of Posterolateral Tibial Plateau Fractures and Poor Functional Outcomes in Type IIIB Impaction Fractures After Anterior Cruciate Ligament Rupture and Reconstruction

Orthopaedic Surgery
Objective The incidence of anterior cruciate ligament (ACL) ruptures has been increasing annually. However, clinical surgeons have overlooked the impaction fractures of the posterolateral tibial plateau and lateral femoral condyle in patients with ACL ...
Shijie Jiang, Weizhi Ren, Ruixia Zhu, Dimitris Dimitriou, Rongshan Cheng, Xiaojun Jia, Dong Zheng, Yuji Wang, Wei Xu   +8 more
doaj   +1 more source

Double-Row Fixation for Avulsion of Anterior Cruciate Ligament

Arthroscopy Techniques, 2019
Avulsion fractures of the tibial spine (also called “tibial eminence fractures” or “ACL avulsion fractures”), leading to discontinuity of anterior cruciate ligament (ACL) fibers, have been well described in the literature in both the pediatric and adult ...
Ziyad Elqirem, M.D., Misbah Alhanbali, M.D., Yazan Sbieh, M.D.   +2 more
doaj   +1 more source

Unstable bicondylar tibial plateau fractures: a clinical investigation

, 2008
OBJECTIVE: To evaluate fracture patterns in bicondylar tibial plateau fractures and their impact on treatment strategy. DESIGN: Prospective data analysis with documentation of initial injury and treatment strategy, computed tomography scans, conventional
Maximilian J Hartel, Christoph Röder, Eggli, S, Haupt, U, Röder, C, Uli Haupt, Sandro Kohl, Aristomenis K Exadaktylos, Exadaktylos, AK, Hartel, MJ, Kohl, S, Stefan Eggli   +11 more
core   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Posteromedial reversed L-shaped approach for posterior column tibial plateau fractures

, 2018
Posterior column tibial plateau fractures are best treated via a posterior approach. Various approaches have been described for reaching the posterior aspect of the tibia plateau: posterolateral, direct posterior, and posteromedial.
Harm Hoekstra, Harm Hoekstra (5678603)
core   +1 more source