Results 51 to 60 of about 61,744 (311)

Knee pain [PDF]

, 2006
JC is a 13 year old boy who presented with a 3 week history of anterior right knee pain. Pain is activity related and brought on whenever JC plays football or basketball. He never needed to stop from any particular activity because of the pain.
Formosa, Aaron
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

TREATMENT OF TRIPLANE FRACTURE ANKLE FRACTURES ASSOCIATED WITH IPSILATERAL TIBIAL FRACTURES USING A NOVEL APPROACH

Acta Ortopédica Brasileira, 2021
Objective: The aim of this study is to purpose a novel approach to the concomitant triplanar and tibial shaft fracture. Methods: Retrospective study between 2001 and 2019. We collected the patients’ general information, clinical and radiographic data,
WEVERLEY RUBELE VALENZA, JAMIL FAISSAL SONI, JEAN CARLO BARBOSA, CHRISTIANO SALIBA ULIANA, CAROLINA UMETA MATSUNAGA   +4 more
doaj   +1 more source

Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study [PDF]

, 2009
Objective: To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after de-training or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury (SCI ...
Coupaud, S., Eser, P., Frotzler, A., Hunt, K.J., Kakebeeke, T.H., Perret, C.   +5 more
core   +2 more sources

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Double-Row Fixation for Avulsion of Anterior Cruciate Ligament

Arthroscopy Techniques, 2019
Avulsion fractures of the tibial spine (also called “tibial eminence fractures” or “ACL avulsion fractures”), leading to discontinuity of anterior cruciate ligament (ACL) fibers, have been well described in the literature in both the pediatric and adult ...
Ziyad Elqirem, M.D., Misbah Alhanbali, M.D., Yazan Sbieh, M.D.   +2 more
doaj   +1 more source

Role of peripheral quantitative computed tomography in identifying disuse osteoporosis in paraplegia [PDF]

, 2009
Objective: Disuse osteoporosis is a major long-term health consequence of spinal cord injury (SCI) that still needs to be addressed. Its management in SCI should begin with accurate diagnosis, followed by targeted treatments in the most vulnerable ...
A Frotzler, A Frotzler, AA Freehafer, Alan N. McLean, B Chen, David B. Allan, ED Bruin de, HH Bolotin, HM Frost, J Rittweger, JL Ferretti, L Giangregorio, L Maimoun, M Bélanger, P Eser, P Eser, P Eser, P Frey-Rindova, P Vestergaard, S Dudley-Javoroski, S-D Jiang, Sylvie Coupaud, T Mohr   +22 more
core   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Positive Pivot Shift Test among Patients with Displaced Anterior Tibial Spine Fractures Undergoing Arthroscopic Fixation in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2023
Introduction: Understanding of displaced anterior tibial spine fractures has evolved over the years and is now considered to be anterior cruciate ligament avulsion injuries rather than intra-articular fractures.
Amit Joshi, Sabin Shrestha, Subhash Regmi, Bibek Basukala, Rajiv Sharma, Rohit Bista, Nagmani Singh, Ishor Pradhan   +7 more
doaj   +1 more source

The first Neanderthal remains from an open-air Middle Palaeolithic site in the Levant [PDF]

, 2017
The late Middle Palaeolithic (MP) settlement patterns in the Levant included the repeated use of caves and open landscape sites. The fossil record shows that two types of hominins occupied the region during this period - Neandertals and Homo sapiens ...
Agha, Nuha, Barash, Alon, Barzilai, Omry, Been, Ella, Benazzi, Stefano, Ekshtain, Ravid, Greenbaum, Noam, Hovers, Erella, Hublin, Jean-Jacques, Levin, Lihi, Malinski-Buller, Ariel, Mayer, Daniella E. Bar-Yosef, Mitki, Netta, Nir, Nadav, Oxilia, Gregorio, Porat, Naomi, Rak, Yoel, Roskin, Joel, Shahack-Gross, Ruth, Soudack, Michalle, Stahlschmidt, Mareike C., Yeshurun, Reuven   +21 more
core   +4 more sources