Results 51 to 60 of about 75,487 (358)

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister   +14 more
wiley   +1 more source

The first Neanderthal remains from an open-air Middle Palaeolithic site in the Levant [PDF]

open access: yes, 2017
The late Middle Palaeolithic (MP) settlement patterns in the Levant included the repeated use of caves and open landscape sites. The fossil record shows that two types of hominins occupied the region during this period - Neandertals and Homo sapiens ...
Agha, Nuha   +21 more
core   +4 more sources

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

open access: yesAdvanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang   +13 more
wiley   +1 more source

External fixation in the treatment of open tibial shaft fractures [PDF]

open access: yes, 2008
Background/Aim. Besides the conquasant fractures, open tibia shaft fractures belong to the group of the most severe fractures of tibia. Open tibia shaft fracture is one of the most common open fractures of long bones.
Golubović Ivan   +13 more
core   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

open access: yesAdvanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon   +21 more
wiley   +1 more source

High Detection Rate of Posterolateral Tibial Plateau Fractures and Poor Functional Outcomes in Type IIIB Impaction Fractures After Anterior Cruciate Ligament Rupture and Reconstruction

open access: yesOrthopaedic Surgery
Objective The incidence of anterior cruciate ligament (ACL) ruptures has been increasing annually. However, clinical surgeons have overlooked the impaction fractures of the posterolateral tibial plateau and lateral femoral condyle in patients with ACL ...
Shijie Jiang   +8 more
doaj   +1 more source

Efficacy of Probiotics for Reducing the Incidence of Lameness in Broilers Grown on Wire Flooring [PDF]

open access: yes, 2013
Growing broilers on wire flooring provides an excellent experimental model for reproducibly triggering significant levels of lameness. In Pilot Study #1 using broilers from Line C grown on wire flooring, adding the Biomin probiotic PoultryStar® to the ...
Stark, John Matthew
core   +2 more sources

Organic Electrochemical Transistors for Neuromorphic Devices and Applications

open access: yesAdvanced Materials, EarlyView.
Organic electrochemical transistors are emerging as promising platforms for neuromorphic devices that emulate neuronal and synaptic activities and can seamlessly integrate with biological systems. This review focuses on resultant organic artificial neurons, synapses, and integrated devices, with an emphasis on their ability to perform neuromorphic ...
Kexin Xiang   +4 more
wiley   +1 more source

Higher fracture prevalence and smaller bone size in patients with hEDS/HSD-a prospective cohort study

open access: yes, 2020
Increased fracture risk in patients with Ehlers-Danlos syndromes has been reported, but the reasons for it are incompletely understood. We aimed to investigate possible determinants of this increased risk and found that hEDS/HSD patients present with a ...
Banica, Thiberiu   +9 more
core   +1 more source

Occult tibial plateau fracture [PDF]

open access: yesBMJ Case Reports, 2017
An 86-year-old woman presented to the emergency department with diffuse left knee pain from a fall from standing height. Anteroposterior and lateral X-ray of the left knee revealed no evidence of a fracture (figure 1A). However, MRI study revealed left tibial plateau fracture (coronal T2-weighted fast field echo imaging (figure 1B) and coronal proton …
Naoki, Yoshida, Yoshihiko, Tsuchida
openaire   +2 more sources

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