Results 61 to 70 of about 12,076 (265)

Posterolateral tibial plateau impaction fractures in patients undergoing primary anterior cruciate ligament reconstruction—An MRI analysis of 556 cases

Journal of Experimental Orthopaedics
Purpose Posterolateral impaction fractures of the tibial plateau are known to be associated with anterior cruciate ligament (ACL) tears. These fractures are often related to high energy pivoting injuries, which is why the frequency of such injuries is of
Andreas Fuchs, Spartak Ovsepyan, Andreas Frodl, Tayfun Yilmaz, Markus Siegel, Matthias Krause, Thomas Stein, Hagen Schmal, Kaywan Izadpanah   +8 more
doaj   +1 more source

Arthroscopic-Assisted Reduction and Percutaneous Fixation of Tibial Plateau Fractures

Arthroscopy Techniques, 2015
Tibial plateau fractures present a difficult range of fractures to treat. Arthroscopy allows for a less invasive option when compared with arthrotomy. Furthermore, visualization of the articular surface arthroscopically can allow for a precise reduction ...
David E. Hartigan, M.D., Mark A. McCarthy, M.D., Aaron J. Krych, M.D., Bruce A. Levy, M.D.   +3 more
doaj   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Persistent Biomechanical Alterations After ACL Reconstruction Are Associated With Early Cartilage Matrix Changes Detected by Quantitative MR. [PDF]

, 2016
BackgroundThe effectiveness of anterior cruciate ligament (ACL) reconstruction in preventing early osteoarthritis is debated. Restoring the original biomechanics may potentially prevent degeneration, but apparent pathomechanisms have yet to be described.
Amano, Keiko, Li, Xiaojuan, Ma, C Benjamin, Pedoia, Valentina, Souza, Richard B, Su, Favian   +5 more
core   +3 more sources

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Meniscus-derived matrix scafolds promote the integrative repair of meniscal defects [PDF]

, 2019
Meniscal tears have a poor healing capacity, and damage to the meniscus is associated with significant pain, disability, and progressive degenerative changes in the knee joint that lead to osteoarthritis.
DeFrate, Louis E., Glass, Katherine A., Guilak, Farshid, McNulty, Amy L., Nishimuta, James F., Rowland, Christopher R., Ruprecht, Jacob C., Stencel, Jennifer, Waanders, Taylor D., Weinberg, J. Brice   +9 more
core   +3 more sources

Analysis of anterior tibial subluxation to the femur at maximum extension in anterior cruciate ligament-deficient knees

Journal of Orthopaedic Surgery, 2019
Purpose: The factors affecting anterior tibial subluxation (ATS) have not yet been well examined. To assess the factors affecting ATS in anterior cruciate ligament (ACL)-deficient knees.
Kyohei Nishida, Takehiko Matsushita, Daisuke Araki, Hiroshi Sasaki, Toshikazu Tanaka, Yuichi Hoshino, Noriyuki Kanzaki, Tomoyuki Matsumoto, Kouki Nagamune, Takahiro Niikura, Masahiro Kurosaka, Ryosuke Kuroda   +11 more
doaj   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source

Correlation of Biomechanical Alterations under Gonarthritis between Overlying Menisci and Articular Cartilage

Applied Sciences, 2020
Just like menisci, articular cartilage is exposed to constant and varying stresses. Injuries to the meniscus are associated with the development of gonarthritis.
Johannes Pordzik, Anke Bernstein, Julius Watrinet, Hermann O. Mayr, Sergio H. Latorre, Hagen Schmal, Michael Seidenstuecker   +6 more
doaj   +1 more source

Posterior tibial slope increases over time in patients undergoing revision ACL reconstruction: A long‐term radiographic follow‐up study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Increased medial posterior tibial slope (PTS) is recognized as a significant risk factor for anterior cruciate ligament reconstruction (ACL‐R) failure. This study investigated radiographic changes in medial PTS over time among skeletally mature individuals undergoing revision ACL‐R and identified associated factors contributing to PTS ...
Mahmut Enes Kayaalp, Jumpei Inoue, Koji Nukuto, Joseph D Giusto, Gillian Ahrendt, Jonathan D. Hughes, James J. Irrgang, Thorkell Snæbjörnsson, Jon Karlsson, Volker Musahl   +9 more
wiley   +1 more source