Results 101 to 110 of about 1,765,538 (343)

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu   +17 more
wiley   +1 more source

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

open access: yesAdvanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani   +20 more
wiley   +1 more source

The Utilization of Plant Growth Regulators (PGRs) in Agricultural Application and The Effecting Mechanisms

open access: yesResearch in Agricultural Sciences
Plants, which lack a sophisticated endocrine system, utilize growth regulators (phytohormones) naturally produced within their bodies to grow, develop, and respond to environmental factors.
Büşra Yirmibeş   +3 more
doaj   +1 more source

Mechanism of Carbon Diffusion and Phase‐Transition‐Induced FCC‐TiC Formation via Hot Pressing

open access: yesAdvanced Science, EarlyView.
A solid‐state diffusion bonding steel‐titanium interface is designed, revealing the formation of continuous micro–nano‐sized FCC‐TiC grains at the interface. Carbon atoms occupying the octahedral interstice in the FCC‐TiC lattice are directly observed.
Sheng Zeng   +5 more
wiley   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Extraction of phenolic compounds and antioxidant activity analysis of Ficus carica L. seed oil using supercritical fluid technology

open access: yesInternational Journal of Plant Based Pharmaceuticals
The rationale behind this study was to investigate the potential of fig (Ficus carica L.) kernel oil as a source of bioactive compounds, particularly focusing on its phenolic compounds, due to the increasing interest in plant-based oils with antioxidant
Osman Burgaz   +5 more
doaj   +1 more source

The Revised TESS Input Catalog and Candidate Target List [PDF]

open access: yes, 2019
We describe the catalogs assembled and the algorithms used to populate the revised TESS Input Catalog (TIC), based on the incorporation of the Gaia second data release. We also describe a revised ranking system for prioritizing stars for 2-minute cadence
Barclay, Thomas   +36 more
core   +3 more sources

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

open access: yesAdvanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang   +8 more
wiley   +1 more source

Ultra‐Thin Oxide‐Based Double‐Layer Architecture Achieves Wide‐Temperature Broadband Microwave Absorption by Synergizing Lorentz Resonance and Thermionic Transport

open access: yesAdvanced Science, EarlyView.
Developing ultrathin wide‐temperature adaptive microwave absorption materials (MAMs) is crucial for enhancing the survival of military devices under alternating high‐temperature environment. Here, a double‐layer La2Zr2O7/Eu2Zr2O7 architecture is employed, with rare‐earth zirconates featuring with one‐eighth anion‐site vacancies, successfully achieving ...
Zewen Duan   +7 more
wiley   +1 more source

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