Results 41 to 50 of about 3,032,984 (321)

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

American Journal of Psychiatry, 2019
OBJECTIVE: Tourette's syndrome is polygenic and highly heritable. Genome-wide association study (GWAS) approaches are useful for interrogating the genetic architecture and determinants of Tourette's syndrome and other tic disorders. The authors conducted
Dongmei Yu, J. Sul, Fotis Tsetsos, Muhammad S. Nawaz, Alden Huang, Ivette Zelaya, C. Illmann, L. Osiecki, S. Darrow, Matthew E. Hirschtritt, E. Greenberg, K. R. Muller-Vahl, M. Stuhrmann, Y. Dion, G. Rouleau, H. Aschauer, Mara Stamenkovic, M. Schlögelhofer, P. Sandor, C. Barr, M. Grados, H. Singer, M. Nöthen, J. Hebebrand, A. Hinney, R. King, T. Fernandez, C. Barta, Z. Tarnok, P. Nagy, C. Depienne, Y. Worbe, A. Hartmann, C. Budman, R. Rizzo, G. Lyon, W. McMahon, J. Batterson, D. Cath, I. Malaty, M. Okun, C. Berlin, D. Woods, Paul C. Lee, J. Jankovic, M. Robertson, D. Gilbert, L. Brown, B. Coffey, A. Dietrich, P. Hoekstra, S. Kuperman, S. Zinner, Pétur Luðvigsson, Evald Sæmundsen, O. Thorarensen, G. Atzmon, N. Barzilai, M. Wagner, R. Moessner, R. Ophoff, C. Pato, M. Pato, J. Knowles, J. Roffman, J. Smoller, R. Buckner, A. Willsey, J. Tischfield, G. Heiman, H. Stefánsson, K. Stefánsson, D. Posthuma, N. Cox, D. Pauls, N. Freimer, B. Neale, L. Davis, P. Paschou, G. Coppola, C. Mathews, J. Scharf   +81 more
semanticscholar   +1 more source

Post-operative adult onset tic disorder: A rare presentation

Indian Journal of Psychological Medicine, 2014
Tics are rapid and repetitive muscle contractions resulting in stereotype movements and vocalizations that are experienced as involuntary. Onset before 18-year is a diagnostic criterion for tic disorders.
Suneet Kumar Upadhyaya, Chintan M Raval, Devendra Kumar Sharma, Devendra Kumar Vijayvergiya   +3 more
doaj   +1 more source

Tackle your Tics: pilot findings of a brief, intensive group-based exposure therapy program for children with tic disorders

European Child and Adolescent Psychiatry, 2020
Tourette syndrome (TS) and other chronic tic disorders (CTD) are prevalent neurodevelopmental disorders, which can have a huge burden on families and society. Behavioral treatment is a first-line intervention for tic disorders.
A. Heijerman-Holtgrefe, C. Verdellen, J. V. D. Griendt, L. Beljaars, K. Kan, D. Cath, P. Hoekstra, C. Huyser, E. Utens, E. Utens   +9 more
semanticscholar   +1 more source

Mechanism of Qihuang needle therapy in the management of tic disorders: a clinical trial protocol

Frontiers in Neurology, 2023
BackgroundQihuang needle therapy is a newly developed acupuncture therapy to treat tic disorders in clinical practice. However, the mechanism to reduce tic severity remains unknown.
Yuyuan Tang, Jun'e Wu, Zhirui Xu, Baochao Fan, Xiangli Li, Bingxu Jin, Chunzhi Tang   +6 more
doaj   +1 more source

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

Angewandte Chemie, EarlyView.
In a study of the biosynthesis of the polyether ionophore lysocellin, the P450 enzyme LyoI was found to catalyze a rare oxidation of a hydro‐2,2′‐bifuran moiety to its hemiketal form. The oxidation was identified as the key for unlocking the bioactivity of lysocellin.
Michelle H. Rasmussen, Søren L. B. Møller, Esben B. Svenningsen, Thomas Tørring, Thomas B. Poulsen   +4 more
wiley   +2 more sources

The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders

Frontiers in Psychiatry, 2020
Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line treatments for tics are antipsychotics and tic-specific behavioral therapies.
E. Jakubovski, Anna Pisarenko, C. Fremer, Martina Haas, M. May, C. Schumacher, Christoph Schindler, S. Häckl, L. Aguirre Dávila, A. Koch, A. Brunnauer, C. Cimpianu, B. Lutz, L. Bindila, K. Müller-Vahl   +14 more
semanticscholar   +1 more source

The New Tics study: A Novel Approach to Pathophysiology and Cause of Tic Disorders

Journal of Psychiatry and Brain Science, 2020
We report on the ongoing project “The New Tics Study: A Novel Approach to Pathophysiology and Cause of Tic Disorders,” describing the work completed to date, ongoing studies and long-term goals.
K. Black, Soyoung Kim, B. Schlaggar, D. Greene   +3 more
semanticscholar   +1 more source

Developing the Premonitory Urges for Tic Disorders Scale-Revised (PUTS-R).

Journal of Neuropsychology, 2020
BACKGROUND Patients with Gilles de la Tourette syndrome (GTS) or chronic tic disorders frequently experience premonitory urges prior to tics. The 'Premonitory Urges for Tic Disorders Scale' (PUTS) is commonly used in order to assess urge severity in ...
Leoni Baumung, K. Müller-Vahl, K. Dyke, G. Jackson, S. Jackson, Dennis Golm, A. Münchau, V. Brandt   +7 more
semanticscholar   +1 more source

Noradrenaline state in children with a tic disorders

Бюллетень сибирской медицины, 2009
The content of noradrenaline in blood serum in 28 children 6–16 years of age with tic disorder was analyzed. It was detected reliable descent the content of noradrenaline in blood serum of the children with a tic disorders compared the group of healthy ...
I. F. Fedoseyeva, T. V. Poponnikova, A. V. Veremeyev   +2 more
doaj   +1 more source

The Pharmacologic Treatment of Tic Disorders

Child and Adolescent Psychiatric Clinics of North America, 1995
The approach to treating children and adolescents with tic disorders has evolved in recent years such that complete elimination of tics is no longer the primary goal of treatment. Indeed, given the high frequency of psychiatric comorbidity in TS, treatment planning begins with identification of target symptoms.
Lawrence Scahill, Phillip B. Chappell, James F. Leckman, Robert A. King   +3 more
openaire   +3 more sources