Results 151 to 160 of about 87,390 (339)

Advanced extracellular vesicle immunotherapy

open access: yesFlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang   +6 more
wiley   +1 more source

Signal transduction in immune cells and extracellular matrix role in viral tick-borne encephalitis

open access: yesИнфекция и иммунитет
Tick-borne encephalitis virus, a member of the genus Orthoflavivirus, consisting of Flaviviridae, is the causative agent of tick-borne encephalitis, a neuroviral disease, the severity of which varies from mild (febrile form) to severe and life ...
Jeanne P. Belokrylova
doaj   +1 more source

Intratumoral bacteria engineered for tumor therapy

open access: yesInterdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang   +7 more
wiley   +1 more source

Quantification of the impact of climate change on animal health: effects on pathogens, vectors, and hosts [PDF]

open access: yes, 2015
Several animal or zoonotic emerging infectious disease (EID) events were recently caused by vector-borne pathogens, e.g. bluetongue virus transmitted by biting midges, or tick-borne encephalitis in Europe.
Lancelot, Renaud
core  

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Increased risk of tick-borne diseases with climate and environmental changes

open access: diamond, 2019
Céline Bouchard   +5 more
openalex   +1 more source

Dynamic coronal plane knee alignment: Femoral anatomy determines kinematic curve morphology, tibial anatomy determines curve position

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose A single hip–knee–ankle angle (HKA) angle does not reflect the biomechanics of native, arthritic or prosthetic knees. Since HKA varies throughout flexion, dynamic coronal alignment is best represented by a kinematic curve plotting HKA against the range of motion.
Petros Ismailidis   +3 more
wiley   +1 more source

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