Results 31 to 40 of about 32,391 (255)

Predominant risk factors for tick-borne co-infections in hunting dogs from the USA

Parasites & Vectors, 2020
Background Both incidence and geographical range of tick-borne disease has increased across the USA. Similar to people, dogs are hosts for Anaplasma spp., Babesia spp., Ehrlichia spp. and Borrelia burgdorferi.
Kurayi Mahachi, Eric Kontowicz, Bryan Anderson, Angela J. Toepp, Adam Leal Lima, Mandy Larson, Geneva Wilson, Tara Grinnage-Pulley, Carolyne Bennett, Marie Ozanne, Michael Anderson, Hailie Fowler, Molly Parrish, Jill Saucier, Phyllis Tyrrell, Zachary Palmer, Jesse Buch, Ramaswamy Chandrashekar, Breanna Scorza, Grant Brown, Jacob J. Oleson, Christine A. Petersen   +21 more
doaj   +1 more source

Ticking on Pandora’s box: a prospective case-control study into ‘other’ tick-borne diseases

BMC Infectious Diseases, 2021
Background Tick-borne pathogens other than Borrelia burgdorferi sensu lato – the causative agent of Lyme borreliosis – are common in Ixodes ricinus ticks. How often these pathogens cause human disease is unknown. In addition, diagnostic tools to identify
D. Hoornstra, M. G. Harms, S. A. Gauw, A. Wagemakers, T. Azagi, K. Kremer, H. Sprong, C. C. van den Wijngaard, J. W. Hovius   +8 more
doaj   +1 more source

Analysis of Microorganism Diversity in Haemaphysalis longicornis From Shaanxi, China, Based on Metagenomic Sequencing

Frontiers in Genetics, 2021
Ticks are dangerous ectoparasites of humans and animals, as they are important disease vectors and serve as hosts for various microorganisms (including a variety of pathogenic microorganisms).
Runlai Cao, Qiaoyun Ren, Jin Luo, Zhancheng Tian, Wenge Liu, Bo Zhao, Jing Li, Peiwen Diao, Yangchun Tan, Xiaofei Qiu, Gaofeng Zhang, Qilin Wang, Guiquan Guan, Jianxun Luo, Hong Yin, Hong Yin, Guangyuan Liu   +16 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A framework for adaptive surveillance of emerging tick-borne zoonoses

One Health, 2019
Significant global ecological changes continue to drive emergence of tick-borne zoonoses around the world. This poses an important threat to both human and animal health, and highlights the need for surveillance systems that are capable of monitoring ...
Katie M. Clow, Patrick A. Leighton, David L. Pearl, Claire M. Jardine   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Hard tick factors implicated in pathogen transmission. [PDF]

PLoS Neglected Tropical Diseases, 2014
Ticks are the most common arthropod vector, after mosquitoes, and are capable of transmitting the greatest variety of pathogens. For both humans and animals, the worldwide emergence or re-emergence of tick-borne disease is becoming increasingly ...
Xiang Ye Liu, Sarah I Bonnet
doaj   +1 more source

Tick-Borne Diseases and Pregnancy: A Narrative Review Evaluating Pregnancy Complications Caused by Tick-Borne Diseases

Tropical Medicine and Infectious Disease
Ticks are vectors of public health concern because the pathogens they transmit can cause detrimental diseases in humans. Lyme disease, tick-borne relapsing fever, human granulocytic anaplasmosis, Rocky Mountain spotted fever, tick-borne encephalitis ...
Michael W. Curtis, Job E. Lopez
doaj   +1 more source

Clinico-epidemiologichesky aspects of the mixed tick-borne infections in the endemic region

Журнал инфектологии, 2014
Detection of clinico-epidemiological features of the mixed tick-borne infections – tick-borne Lyme disease and a human granulocytic anaplasmosis was the purpose of the conducted research.
E. S. Aleshkovskaya, N. A. Blagov, V. A. Bazunova   +2 more
doaj   +1 more source